M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC 50 value of 0.09 u202fμM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC 50 values of u202f0.53u202f μM and 1.39 μM, resp
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Product Description
M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC 50 value of 0.09 μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC 50 values of 0.53 μM and 1.39 μM, respectively. M2N12 has anti-tumor activity and can be used for cancer research.
In Vitro
M2N12 (0-20 μM; 72 hours) has cytotoxic activity against five tumor cell lines and a normal cell line including A-549, MDA-MB-231, KB, KB-VIN, MCF-7 and HBE (IC 50 =3.92 μM, 4.63 μM, 5.05 μM, 6.81 μM, 4.71 μM and 6.00 μM, respectively). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
