M344 - ≥97%, high purity , CAS No.251456-60-7

Item Number

M125894

• Synonyms: EC-000.2275 | N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide | CS-1342 | Histone Deacetylase Inhibitor III | AS-71316 | C74302 | CHEBI:125562 | 4-Dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide | 4-DIMETHYLAMINO-N-(6-HYDROXYCARBAMOYLHEXYL)-BENZAM
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: M344 is a potent HDAC inhibitor (IC50 = 100 nM), with selectivity for HDAC6 over HDAC1. M344 induces terminal cell differentiation and causes an increase in hyperacetylated histone H4. It also induces cell cycle arrest and apoptosis in human endometrial a
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

M344 is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.
A potent HDAC inhibitor with IC50 of 100.