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MA-0204 - 98%, high purity , CAS No.2095128-17-7

  • ≥98%
Item Number
M412414
Grouped product items
SKUSizeAvailabilityPrice Qty
M412414-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$64.90
M412414-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$259.90
M412414-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90
M412414-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,187.90
M412414-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,129.90
View related series
PPAR

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsMA-0204 is a potent, highly selective and orally available modulator of peroxisome proliferator activated receptor δ (PPARδ) with\xa0EC50 of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. MA-0204 is used as a potential treatment fo
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

MA-0204 is a potent, highly selective and orally available modulator of peroxisome proliferator activated receptor δ (PPARδ) with EC50 of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. MA-0204 is used as a potential treatment for Duchene Muscular Dystrophy (DMD).

Associated Targets

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PGR Tclin Progesterone receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARA Tclin Peroxisome proliferator-activated receptor alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARD Tchem Peroxisome proliferator-activated receptor delta 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (3R)-3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethoxy)phenyl]imidazol-1-yl]methyl]phenoxy]hexanoic acid
INCHI InChI=1S/C25H27F3N2O4/c1-17(14-23(31)32)6-5-13-33-22-8-4-3-7-20(22)16-30-18(2)15-29-24(30)19-9-11-21(12-10-19)34-25(26,27)28/h3-4,7-12,15,17H,5-6,13-14,16H2,1-2H3,(H,31,32)/t17-/m1/s1
InChi Key GYNMVDMBFKGCCR-QGZVFWFLSA-N
Canonical SMILES CC1=CN=C(N1CC2=CC=CC=C2OCCCC(C)CC(=O)O)C3=CC=C(C=C3)OC(F)(F)F
Isomeric SMILES CC1=CN=C(N1CC2=CC=CC=C2OCCC[C@@H](C)CC(=O)O)C3=CC=C(C=C3)OC(F)(F)F
PubChem CID 126752361
Molecular Weight 476.49

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Certificate of Analysis(COA)

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9 results found

Lot NumberCertificate TypeDateItem
G2415454Certificate of AnalysisApr 01, 2024 M412414
G2415455Certificate of AnalysisApr 01, 2024 M412414
G2415457Certificate of AnalysisApr 01, 2024 M412414
G2415458Certificate of AnalysisApr 01, 2024 M412414
G2415459Certificate of AnalysisApr 01, 2024 M412414
G2415460Certificate of AnalysisApr 01, 2024 M412414
G2415461Certificate of AnalysisApr 01, 2024 M412414
G2415462Certificate of AnalysisApr 01, 2024 M412414
G2415463Certificate of AnalysisApr 01, 2024 M412414

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