Basic Description

Synonyms	BDBM50480484 \| SCHEMBL16227189 \| 1,7-DIHYDROXY-3-METHOXY-6-METHYL-9,10-DIHYDROANTHRACENE-9,10-DIONE \| 9,10-Anthracenedione, 1,7-dihydroxy-3-methoxy-6-methyl- \| 1,7-dihydroxy-3-methoxy-6-methyl-9,10-anthraquinone \| J-014592 \| DTXSID50176769 \| Macrosporin \|
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Macrosporin is an anthraquinone antibiotic. Macrosporin is described to produce antibacterial growth inhibition against\|Bacillus subtilis\|and\|Staphylococcus aureus\|in agar diffusion assays.

Associated Targets(Human)

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)

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INSR Tclin Insulin receptor (5558 Activities)

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ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)

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PDGFRB Tclin Platelet-derived growth factor receptor beta (5195 Activities)

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IGF1R Tclin Insulin-like growth factor I receptor (8605 Activities)

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CSNK2A1 Tchem Casein kinase II alpha (3512 Activities)

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SRC Tclin Tyrosine-protein kinase SRC (10310 Activities)

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AURKB Tchem Serine/threonine-protein kinase Aurora-B (6805 Activities)

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PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)

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KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

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PTK2 Tclin Focal adhesion kinase 1 (4730 Activities)

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MET Tclin Hepatocyte growth factor receptor (10718 Activities)

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CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)

Discover Target: CDK2

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FLT4 Tclin Vascular endothelial growth factor receptor 3 (3216 Activities)

Discover Target: FLT4

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AKT1 Tchem Serine/threonine-protein kinase AKT (9192 Activities)

Discover Target: AKT1

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FLT3 Tclin Tyrosine-protein kinase receptor FLT3 (13481 Activities)

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TEK Tclin Tyrosine-protein kinase TIE-2 (3348 Activities)

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AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)

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PLK4 Tchem Serine/threonine-protein kinase PLK4 (1882 Activities)

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A549 (127892 Activities)

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BRAF Tclin Serine/threonine-protein kinase B-raf (11587 Activities)

Discover Target: BRAF

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EPHB4 Tchem Ephrin type-B receptor 4 (3198 Activities)

Discover Target: EPHB4

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MAP3K8 Tchem Mitogen-activated protein kinase kinase kinase 8 (459 Activities)

Discover Target: MAP3K8

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NUAK1 Tchem NUAK family SNF1-like kinase 1 (1769 Activities)

Discover Target: NUAK1

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CDK4 Tclin Cyclin-dependent kinase 4/cyclin D1 (2340 Activities)

Discover Target: CDK4

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Associated Targets(non-human)

Vibrio parahaemolyticus (473 Activities)

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Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Staphylococcus (1598 Activities)

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Aspergillus flavus (8875 Activities)

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Bacillus subtilis (32866 Activities)

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Bacillus cereus (7522 Activities)

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L5178Y (1809 Activities)

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Fusarium verticillioides (912 Activities)

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Micrococcus (119 Activities)

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Kocuria rhizophila (337 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1,7-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione
INCHI	InChI=1S/C16H12O5/c1-7-3-9-10(6-12(7)17)16(20)14-11(15(9)19)4-8(21-2)5-13(14)18/h3-6,17-18H,1-2H3
InChi Key	FKTPLNFTYJEAAB-UHFFFAOYSA-N
Canonical SMILES	CC1=CC2=C(C=C1O)C(=O)C3=C(C2=O)C=C(C=C3O)OC
Isomeric SMILES	CC1=CC2=C(C=C1O)C(=O)C3=C(C2=O)C=C(C=C3O)OC
PubChem CID	159926
Molecular Weight	284.26

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	Soluble in DMSO or 100% ethanol.

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Macrosporin , CAS No.22225-67-8

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator