MAGL-IN-5 - 99%, high purity , CAS No.359714-55-9

  • ≥99%
Item Number
M649920
Grouped product items
SKUSizeAvailabilityPrice Qty
M649920-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$80.90
M649920-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$130.90
M649920-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$260.90
M649920-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$410.90
M649920-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$650.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsMAGL-IN-5 (CAY10499) is a non-selective lipase inhibitor with IC 50 values of 144, 90, and 14 nM for human recombinant monoacylglycerol lipase(MAGL) , hormone sensitive lipase(HSL) , and fatty acid amide hydrolase(FAAH) respectively.
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

MAGL-IN-5 (CAY10499) is a non-selective lipase inhibitor with IC 50 values of 144, 90, and 14 nM for human recombinant monoacylglycerol lipase(MAGL) , hormone sensitive lipase(HSL) , and fatty acid amide hydrolase(FAAH) respectively.

Form:Solid

Associated Targets(Human)

FAAH Tchem Fatty-acid amide hydrolase 1 (6 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MGLL Tchem Monoglyceride lipase (21 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MRC5 (9203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OVCAR-3 (48710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SK-OV-3 (52876 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Caov-3 cell line (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MGLL Tchem Monoglyceride lipase (1909 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name benzyl N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamate
INCHI InChI=1S/C18H17N3O5/c1-12-10-14(21-18(23)26-17(20-21)24-2)8-9-15(12)19-16(22)25-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3,(H,19,22)
InChi Key QTENHWTVRQKWRI-UHFFFAOYSA-N
Canonical SMILES CC1=C(C=CC(=C1)N2C(=O)OC(=N2)OC)NC(=O)OCC3=CC=CC=C3
Isomeric SMILES CC1=C(C=CC(=C1)N2C(=O)OC(=N2)OC)NC(=O)OCC3=CC=CC=C3
PubChem CID 9924775
MeSH Entry Terms CAY 10499;CAY-10499;CAY10499
Molecular Weight 355.34

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (281.42 mM; Need ultrasonic)

Related Documents

Solution Calculators