Makisterone A - ≥95%, high purity , CAS No.20137-14-8

  • ≥95%
Item Number
M275594
Grouped product items
SKUSizeAvailabilityPrice Qty
M275594-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$209.90
M275594-250μg
250μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$67.90
M275594-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$513.90

Potent ecdysone receptor (EcR) agonist

Basic Description

SynonymsMakisterone A | 20137-14-8 | Makisteron A | CHEMBL255034 | CHEBI:80775 | Ergost-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2beta,3beta,5beta,22R,24R)- | Ergost-7-en-b-one, 2,3,14,20,22,25-hexahydroxy-, (2beta,3beta,5beta,22R,24R)- | (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14
Specifications & Purity≥95%
Biochemical and Physiological MechanismsPotent ecdysone receptor (EcR) agonist. Shows similar affinity for EcR as 20-Hydroxyecdysone Predominant insect moulting hormone in vivo.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

EcR Ecdysone receptor (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R,5R)-2,3,6-trihydroxy-5,6-dimethylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
INCHI InChI=1S/C28H46O7/c1-15(24(2,3)33)11-23(32)27(6,34)22-8-10-28(35)17-12-19(29)18-13-20(30)21(31)14-25(18,4)16(17)7-9-26(22,28)5/h12,15-16,18,20-23,30-35H,7-11,13-14H2,1-6H3/t15-,16+,18+,20-,21+,22+,23-,25-,26-,27-,28-/m1/s1
InChi Key IJRBORPEVKCEQD-JMQWOFAPSA-N
Canonical SMILES CC(CC(C(C)(C1CCC2(C1(CCC3C2=CC(=O)C4C3(CC(C(C4)O)O)C)C)O)O)O)C(C)(C)O
Isomeric SMILES C[C@H](C[C@H]([C@@](C)([C@H]1CC[C@@]2([C@@]1(CC[C@H]3C2=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)C)O)O)O)C(C)(C)O
PubChem CID 12312690
Molecular Weight 494.66

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in ethanol and in DMSO

Related Documents

Solution Calculators