K2130461Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | AB00640020-06 | MALEIC ACID [WHO-DD] | SODIUM AUROTHIOMALATE IMPURITY A [EP IMPURITY] | 1,2-Ethylenedicarboxylic acid, cis- | bmse000212 | MALEIC ACID [MI] | bis-hydrogen maleate | HY-Y0367 | AI3-01002 | Malezid CM | NCGC00090970-02 | (2Z)-2-Butenedioic a |
|---|---|
| Specifications & Purity | pharmaceutical grade, PharmPure™, Ph.Eur., USP |
| Shipped In | Normal |
| Grade | Ph.Eur., pharmaceutical grade, PharmPure™, USP |
| Action Type | AGONIST |
| Mechanism of action | Agonist of succinate receptor |
Associated Targets(Human)
SUCNR1 Tchem Succinate receptor 1 (3 Activities)
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ME3 Tbio NADP-dependent malic enzyme, mitochondrial (80 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ERG Tbio Transcriptional regulator ERG (5589 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GMNN Tbio Geminin (128009 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SARS-CoV-2 (38078 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Names and Identifiers
| IUPAC Name | (Z)-but-2-enedioic acid |
|---|---|
| INCHI | InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1- |
| InChi Key | VZCYOOQTPOCHFL-UPHRSURJSA-N |
| Canonical SMILES | C(=CC(=O)O)C(=O)O |
| Isomeric SMILES | C(=C\C(=O)O)\C(=O)O |
| WGK Germany | 1 |
| PubChem CID | 444266 |
| UN Number | 2215 |
| Packing Group | III |
| Molecular Weight | 116.07 |
| Beilstein | 605762 |
Database links
| CAS Registry No. | 110-16-7 |
|---|---|
| PubChem CID | 444266 |
| Wikipedia | Maleic_acid |
| RCSB PDB Ligand | MAE |
| GPCRdb Ligand | maleic acid |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Solubility | Soluble in water, soluble in ethanol and acetone, slightly soluble in benzene. |
|---|---|
| Sensitivity | Moisture sensitive. |
| Flash Point(°F) | 260.6℉ |
| Flash Point(°C) | 127℃ |
| Melt Point(°C) | 138-139°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H317:May cause an allergic skin reaction |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 1 |
| Class | 8 |
| Merck Index | 5703 |
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