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Malic acid - meets USP/NF testing specifications, high purity , CAS No.6915-15-7

49 Citations
Item Number
M433327
Grouped product items
SKUSizeAvailabilityPrice Qty
M433327-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
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Basic Description

SynonymsMALIC ACID (USP-RS) | Hydroxybutanedioic acid, (-)- | Butanedioic acid, hydroxy- | DL-2-hydroxybutanedioic acid | E296 | E-296 | MALIC ACID,(DL) | NSC25941 | NSC-25941 | (+-)-Hydroxysuccinic acid | 2-Hydroxysuccinic acid | 2-HYDROXY-SUCCINIC ACID | hydrox
Specifications & PurityPharmPure™, USP, NF
GradeNF, PharmPure™, USP
Product Description

Malic acid is a dicarboxylic acid that can be prepared by hydration of maleic acid or fumaric acid. Its ability to prevent the oxidative degradation of lipids has been assessed. The impact of malic acid in the alteration of calcium chloride crystal morphology has been studied. The dissolution kinetics of kaolinite in malic acid have been reported. This product is a high quality pharmacopoeia product that meets the testing specifications of USP (United States Pharmacopoeia). It can be employed in research and pilot studies.

Associated Targets(Human)

PKD2L1 Tchem Polycystic kidney disease 2-like 1 protein (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGLN2 Tclin Hypoxia-inducible factor prolyl hydroxylase 1 (404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGLN1 Tclin Egl nine homolog 1 (1702 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGLN3 Tclin Egl nine homolog 3 (250 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HIF1AN Tbio Hypoxia-inducible factor 1-alpha inhibitor (79 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (473 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meloidogyne incognita (862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-hydroxybutanedioic acid
INCHI InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
InChi Key BJEPYKJPYRNKOW-UHFFFAOYSA-N
Canonical SMILES C(C(C(=O)O)O)C(=O)O
Isomeric SMILES C(C(C(=O)O)O)C(=O)O
WGK Germany 3
RTECS ON7175000
Alternate CAS 617-48-1
PubChem CID 525
Molecular Weight 134.09
Beilstein 1723539
Reaxy-Rn 1723539

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Melt Point(°C)129-133°C

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H318:Causes serious eye damage

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

WGK Germany 3
RTECS ON7175000
Reaxy-Rn 1723539
Merck Index 5707

Related Documents

 SDS

 Specification Sheet

Citations of This Product

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29. Rong Wu, Qihui Dong, Ziyan Che, Huimin Wang, Jun Cao, Fuliang Cao, Erzheng Su.  (2022)  Green and Efficient Simultaneous Enrichment and Separation of Multiple Valuable Bioactive Compounds from Agricultural Waste Ginkgo biloba Exocarp Using a Two-Phase Deep Eutectic Solvent System.  ACS Sustainable Chemistry & Engineering,  10  (50): (16958–16968).  [PMID:]
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46. Jia Chen, Shuying Han, Mengjia Huang, Jie Li, Mi Zhou, Jianguo He.  (2022)  Green crosslinked nanofibers membrane based on CS/PVA combined with polybasic organic acid for tympanic membrane repair.  International Journal of Polymeric Materials and Polymeric Biomaterials,      [PMID:]
47. Kunlin Liu, Jia-Neng Tan, Yulei Wei, Changkun Li, Yuqing Dou, Zhongfeng Zhang.  (2022)  Application of choline chloride-based deep eutectic solvents for the extraction of dopamine from purslane (Portulaca oleracea L.).  Results in Chemistry,  4  (100299).  [PMID:]
48. Zi Ye, Zhixun Shang, Shiyao Zhang, Meiqi Li, Xuetin Zhang, Hongbing Ren, Xiaosong Hu, Junjie Yi.  (2022)  Dynamic analysis of flavor properties and microbial communities in Chinese pickled chili pepper (Capsicum frutescens L.): A typical industrial-scale natural fermentation process.  FOOD RESEARCH INTERNATIONAL,  153  (110952).  [PMID:35227474]
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92. Xianchao Shang, Manman Zhang, Jing Hu, Yuqin Zhang, Long Yang, Xin Hou.  (2023)  Chemical Compositions, Extraction Optimizations, and In Vitro Bioactivities of Flavonoids from Perilla Leaves (Perillae folium) by Microwave-Assisted Natural Deep Eutectic Solvents.  Antioxidants,  12  (1): (104).  [PMID:36670966]
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94. Lianghui Gong, Shuaipeng Wang, Jingyuan Hu, Haoyang Feng, Li Zhang, Jinyue Dai, Xiaoqin Liu.  (2023)  A novel bio-based degradable, reinforced vitrimer regulated by intramolecular hydrogen bonding.  PROGRESS IN ORGANIC COATINGS,  175  (107384).  [PMID:]
95. Rong Wu, Qihui Dong, Ziyan Che, Huimin Wang, Jun Cao, Fuliang Cao, Erzheng Su.  (2022)  Green and Efficient Simultaneous Enrichment and Separation of Multiple Valuable Bioactive Compounds from Agricultural Waste Ginkgo biloba Exocarp Using a Two-Phase Deep Eutectic Solvent System.  ACS Sustainable Chemistry & Engineering,  10  (50): (16958–16968).  [PMID:]
96. Yongjing Liu, Suxia Zhang, Li Lou, Tang Yan, Wei Xu.  (2022)  Evaluating the behavior and principle of deep eutectic solvent on ephedrine-type alkaloid extraction from Ephedrae Herba.  BIOMEDICAL CHROMATOGRAPHY,  37  (2): (e5541).  [PMID:36328792]
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98. Man Zhang, Xiaomeng Zhao, Siyang Tang, Kejing Wu, Binshen Wang, Yingying Liu, Yingming Zhu, Houfang Lu, Bin Liang.  (2023)  Structure–properties relationships of deep eutectic solvents formed between choline chloride and carboxylic acids: Experimental and computational study.  JOURNAL OF MOLECULAR STRUCTURE,  1273  (134283).  [PMID:]
99. Rong Yang, Guozhang Gu, Mengdi Li, Jinchun Li.  (2022)  Preparation of flame-retardant rigid polyurethane foam with bio-based phosphorus-containing polyols and expandable graphite.  JOURNAL OF APPLIED POLYMER SCIENCE,  139  (46): (e53167).  [PMID:]
100. Yuqin Zhang, Shiquan Bian, Jing Hu, Gang Liu, Shouhua Peng, Hongjiang Chen, Zhenying Jiang, Tongyong Wang, Quan Ye, Haibo Zhu.  (2022)  Natural Deep Eutectic Solvent-Based Microwave-Assisted Extraction of Total Flavonoid Compounds from Spent Sweet Potato (Ipomoea batatas L.) Leaves: Optimization and Antioxidant and Bacteriostatic Activity.  MOLECULES,  27  (18): (5985).  [PMID:36144716]
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111. Dan Cao, Min Liu, Yung-Chih Su, Zehui Yang, Wentao Bi, David Da Yong Chen.  (2022)  Adsorption behavior of anthraquinones in deep eutectic solvent on polyester fiber and its application.  Sustainable Chemistry and Pharmacy,  27  (100680).  [PMID:]
112. Jia Chen, Shuying Han, Mengjia Huang, Jie Li, Mi Zhou, Jianguo He.  (2022)  Green crosslinked nanofibers membrane based on CS/PVA combined with polybasic organic acid for tympanic membrane repair.  International Journal of Polymeric Materials and Polymeric Biomaterials,      [PMID:]
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