Maprotiline , CAS No.10262-69-8, Channel blocker of K ir3.2;Channel blocker of K ir3.4;Inhibitor of NET;Channel blocker of TRPM3

Item Number

M338146

Grouped product items
SKU	Size	Availability	Price	Qty
M338146-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$532.90

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Basic Description

Synonyms	Maprotylina \| DB00934 \| 3-(9,10-ethanoanthracen-9(10H)-yl)-N-methylpropan-1-amine \| NCGC00015708-05 \| NCGC00015708-11 \| BDBM50378025 \| HMS2089K11 \| NCGC00015708-13 \| NCGC00015708-02 \| NCGC00016691-01 \| SPBio_002332 \| KBio2_001367 \| Maprotilina [INN-Spanis
Specifications & Purity	Moligand™
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	CHANNEL BLOCKER, INHIBITOR
Mechanism of action	Channel blocker of K ir3.2;Channel blocker of K ir3.4;Inhibitor of NET;Channel blocker of TRPM3

Associated Targets(Human)

TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNJ6 Tchem G protein-activated inward rectifier potassium channel 2 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor (3 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A2 Tclin Sodium-dependent noradrenaline transporter (4 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM4 Tclin Muscarinic acetylcholine receptor M4 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A (2 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2C Tclin 5-hydroxytryptamine receptor 2C (2 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNJ5 Tchem G protein-activated inward rectifier potassium channel 4 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
INCHI	InChI=1S/C20H23N/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20/h2-5,7-10,15,21H,6,11-14H2,1H3
InChi Key	QSLMDECMDJKHMQ-UHFFFAOYSA-N
Canonical SMILES	CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24
Isomeric SMILES	CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24
PubChem CID	4011
Molecular Weight	277.4
Beilstein	2385493