The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Your company account is blocked and you cannot place orders. If you have questions, please contact your company administrator.
maribavir , Phosphotransferase pUL97 inhibitor, CAS No.176161-24-3, Phosphotransferase pUL97 inhibitor
Basic Description Synonyms 5,6-Dichloro-2-(isopropylamino)-1-(beta-L-ribofuranosyl)-1H-benzimidazole | 5,6-DICHLORO-2-(ISOPROPYLAMINO)-1-.BETA.-L-RIBOFURANOSYLBENZIMIDAZOLE | Maribavir | maribavirum | F20066 | GW-1263 | cis-3,5-dimethylpiperazine-1-carboxylic acid tert-butyl ester Specifications & Purity Moligand™ Grade Moligand™ Action Type INHIBITOR Mechanism of action Phosphotransferase pUL97 inhibitor
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References The page will load shortly, Thanks for your patience!
Names and Identifiers IUPAC Name (2S,3S,4R,5S)-2-[5,6-dichloro-2-(propan-2-ylamino)benzimidazol-1-yl]-5-(hydroxymethyl)oxolane-3,4-diol INCHI InChI=1S/C15H19Cl2N3O4/c1-6(2)18-15-19-9-3-7(16)8(17)4-10(9)20(15)14-13(23)12(22)11(5-21)24-14/h3-4,6,11-14,21-23H,5H2,1-2H3,(H,18,19)/t11-,12-,13-,14-/m0/s1 InChi Key KJFBVJALEQWJBS-XUXIUFHCSA-N Canonical SMILES CC(C)NC1=NC2=CC(=C(C=C2N1C3C(C(C(O3)CO)O)O)Cl)Cl Isomeric SMILES CC(C)NC1=NC2=CC(=C(C=C2N1[C@@H]3[C@H]([C@H]([C@@H](O3)CO)O)O)Cl)Cl PubChem CID 471161 Molecular Weight 376.24
Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 376.200 g/mol XLogP3 2.200 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 4 Exact Mass 375.075 Da Monoisotopic Mass 375.075 Da Topological Polar Surface Area 99.800 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 447.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 4 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
References 1. Biron KK, Harvey RJ, Chamberlain SC, Good SS, Smith 3rd AA, Davis MG, Talarico CL, Miller WH, Ferris R, Dornsife RE et al. . (2002) Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action.. Antimicrob Agents Chemother, 46 (8): (2365-72). [PMID:12121906 ] [10.1021/op500134e ] 2. Kang C. (2022) Maribavir: First Approval.. Drugs, 82 (3): (335-340). [PMID:35147913 ] [10.1021/op500134e ]
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
