K2221067Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | AKOS000283004 | Matairesinol, >=85% (HPLC) | A831721 | Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-(3R,4R)-2(3H)-Furanone | ACon1_001075 | DTXCID301349397 | NCGC00169701-01 | (-)-Matairesinol | MEGxp0_001689 | SR-01000946700-1 | UNII-XLW63P8WUA | 2 |
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| Specifications & Purity | ≥98% |
| Storage Temp | Store at -20°C,Argon charged |
| Shipped In | Ice chest + Ice pads |
| Product Description | Matairesinol is one of the principle lignands present in dietary fiber. Metabolized by enteric bacteria to enterolactone and enterodiol. Matairesinol displays an inverse association between serum enterolactone levels and serum isoprostane levels. This implies a protective effect against oxidative injury. Matairesinol is an inhibitor of Mdr-1. |
Product Properties
| pKa | pKa: 10.02 |
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Associated Targets(Human)
SHBG Tchem Sex hormone-binding globulin (1 Activities)
HL-60 (67320 Activities)
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SK-MEL-2 (46422 Activities)
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SK-OV-3 (52876 Activities)
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XF498 (12972 Activities)
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A549 (127892 Activities)
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H9 (1832 Activities)
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HepG2 (196354 Activities)
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HeLa (62764 Activities)
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BL-41 (110 Activities)
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Associated Targets(non-human)
Ttr Transthyretin (14 Activities)
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Shbg Testis-specific androgen-binding protein (10 Activities)
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pol Human immunodeficiency virus type 1 integrase (9041 Activities)
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Aspergillus niger (16508 Activities)
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Penicillium (212 Activities)
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Human alphaherpesvirus 1 (11089 Activities)
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Human immunodeficiency virus 1 (70413 Activities)
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rhinovirus A1B (360 Activities)
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Vesicular stomatitis virus (4460 Activities)
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RAW264.7 (28094 Activities)
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BV-2 (3710 Activities)
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (3R,4R)-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one |
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| INCHI | InChI=1S/C20H22O6/c1-24-18-9-12(3-5-16(18)21)7-14-11-26-20(23)15(14)8-13-4-6-17(22)19(10-13)25-2/h3-6,9-10,14-15,21-22H,7-8,11H2,1-2H3/t14-,15+/m0/s1 |
| InChi Key | MATGKVZWFZHCLI-LSDHHAIUSA-N |
| Canonical SMILES | COC1=C(C=CC(=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)O |
| Isomeric SMILES | COC1=C(C=CC(=C1)C[C@H]2COC(=O)[C@@H]2CC3=CC(=C(C=C3)O)OC)O |
| WGK Germany | 3 |
| PubChem CID | 119205 |
| Molecular Weight | 358.39 |
| Beilstein | 7826317 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Solubility | Soluble in water (0.25 mg/ml) at 25° C, ethanol (2 mg/ml), DMSO (30 mg/ml), DMSO:PBS(PH7.2)(1:4) (0.25 mg/ml), and DMF (30 mg/ml). |
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| Sensitivity | Moisture sensitive |
| Refractive Index | n20D1.61 |
| Boil Point(°C) | ~593.0° C at 760 mmHg (Predicted) |
| Melt Point(°C) | 225.16° C (Predicted) |
Safety and Hazards(GHS)
| WGK Germany | 3 |
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