Skip to the beginning of the images gallery

mavoglurant , Metabotropic glutamate receptor 5 antagonist, CAS No.543906-09-8, Metabotropic glutamate receptor 5 antagonist

Moligand™

CAS#: 543906-09-8
Formula: C₁₉H₂₃NO₃
Molecular Weight: 313.39
PubChem CID: 9926832

Item Number

M611748

Grouped product items
SKU	Size	Availability	Price	Qty
M611748-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,300.90
M611748-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

Basic Description

Synonyms	Mavoglurant\|543906-09-8\|AFQ056\|AFQ-056\|(3ar,4s,7ar)-octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1h-indole-1-carboxylic acid methyl ester\|GT0I9SV4F6\|methyl (3aR,4S,7aR)-4-hydroxy-4-(m-tolylethynyl)octahydro-1H-indole-1-carboxylate\|1H-Indole-1-carboxy
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Metabotropic glutamate receptor 5 antagonist

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM5 Tchem Metabotropic glutamate receptor 5 4 Activities

Discover Target: GRM5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	methyl (3aR,4S,7aR)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-3,3a,5,6,7,7a-hexahydro-2H-indole-1-carboxylate
INCHI	InChI=1S/C19H23NO3/c1-14-5-3-6-15(13-14)8-11-19(22)10-4-7-17-16(19)9-12-20(17)18(21)23-2/h3,5-6,13,16-17,22H,4,7,9-10,12H2,1-2H3/t16-,17-,19-/m1/s1
InChi Key	ZFPZEYHRWGMJCV-ZHALLVOQSA-N
Canonical SMILES	CC1=CC(=CC=C1)C#CC2(CCCC3C2CCN3C(=O)OC)O
Isomeric SMILES	CC1=CC(=CC=C1)C#C[C@@]2(CCC[C@@H]3[C@H]2CCN3C(=O)OC)O
PubChem CID	9926832
Molecular Weight	313.39

CAS Registry No.

PubChem CID

Wikipedia

ChEMBL Ligand

RCSB PDB Ligand

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS09
Signal	Warning
Hazard Statements	H373:Causes damage to organs through prolonged or repeated exposure H411:Toxic to aquatic life with long lasting effects H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P260:Do not breathe dust/fume/gas/mist/vapors/spray. P391:Collect spillage. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell.

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

mavoglurant , Metabotropic glutamate receptor 5 antagonist, CAS No.543906-09-8, Metabotropic glutamate receptor 5 antagonist

Basic Description

Product Properties

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

GRM5 Tchem Metabotropic glutamate receptor 5 4 Activities

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Safety and Hazards(GHS)

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator