MCHr1 antagonist 2 - 98%, high purity , CAS No.863115-70-2

  • ≥98%
Item Number
M412388
Grouped product items
SKUSizeAvailabilityPrice Qty
M412388-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
M412388-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$219.90
M412388-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
M412388-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,236.90
M412388-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,119.90

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsMCHr1 antagonist 2 is a melanin concentrating hormone receptor 1 antagonist with IC50 of 65 nM. MCHr1 antagonist 2 also inhibits hERG with IC50 of 4.0 nM in IMR-32 cells.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

MCHr1 antagonist 2 is a melanin concentrating hormone receptor 1 antagonist with IC50 of 65 nM. MCHr1 antagonist 2 also inhibits hERG with IC50 of 4.0 nM in IMR-32 cells.

Associated Targets(Human)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MCHR1 Tchem Melanin-concentrating hormone receptor 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCHR1 Tchem Melanin-concentrating hormone receptor 1 (5587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-4-oxochromene-2-carboxamide
INCHI InChI=1S/C23H21FN2O5/c24-15-2-4-19-17(10-15)18(27)11-22(31-19)23(28)25-16-5-7-26(8-6-16)12-14-1-3-20-21(9-14)30-13-29-20/h1-4,9-11,16H,5-8,12-13H2,(H,25,28)
InChi Key HHCYCBKPWYJVEB-UHFFFAOYSA-N
Canonical SMILES C1CN(CCC1NC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)F)CC4=CC5=C(C=C4)OCO5
Isomeric SMILES C1CN(CCC1NC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)F)CC4=CC5=C(C=C4)OCO5
PubChem CID 11464405
Molecular Weight 424.42

Certificates

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10 results found

Lot NumberCertificate TypeDateItem
D2419471Certificate of AnalysisFeb 05, 2024 M412388
D2419473Certificate of AnalysisFeb 05, 2024 M412388
D2419474Certificate of AnalysisFeb 05, 2024 M412388
D2419475Certificate of AnalysisFeb 05, 2024 M412388
D2419476Certificate of AnalysisFeb 05, 2024 M412388
D2419477Certificate of AnalysisFeb 05, 2024 M412388
D2419478Certificate of AnalysisFeb 05, 2024 M412388
D2419479Certificate of AnalysisFeb 05, 2024 M412388
D2419480Certificate of AnalysisFeb 05, 2024 M412388
D2419482Certificate of AnalysisFeb 05, 2024 M412388

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