MCL-1/BCL-2-IN-3 - 99%, high purity , CAS No.2163793-55-1

  • ≥99%
Item Number
M649688
Grouped product items
SKUSizeAvailabilityPrice Qty
M649688-2mg
2mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$166.90
M649688-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$350.90
M649688-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$650.90
M649688-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$990.90
M649688-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,650.90
M649688-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,250.90
View related series
Apoptosis Bcl-2 Family

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsMCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC 50 s of 5.95 and 4.78 μM, respectively.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC 50 s of 5.95 and 4.78 μM, respectively.

Form:Solid

Associated Targets(Human)

BCL2 Tclin Apoptosis regulator Bcl-2 (3787 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name methyl 6-[2-[6-(4-bromophenyl)sulfanyl-1,3-dioxobenzo[de]isoquinolin-2-yl]ethylamino]-6-oxohexanoate
INCHI InChI=1S/C27H25BrN2O5S/c1-35-24(32)8-3-2-7-23(31)29-15-16-30-26(33)20-6-4-5-19-22(14-13-21(25(19)20)27(30)34)36-18-11-9-17(28)10-12-18/h4-6,9-14H,2-3,7-8,15-16H2,1H3,(H,29,31)
InChi Key HZZXWFWVQWMGAR-UHFFFAOYSA-N
Canonical SMILES COC(=O)CCCCC(=O)NCCN1C(=O)C2=C3C(=C(C=C2)SC4=CC=C(C=C4)Br)C=CC=C3C1=O
Isomeric SMILES COC(=O)CCCCC(=O)NCCN1C(=O)C2=C3C(=C(C=C2)SC4=CC=C(C=C4)Br)C=CC=C3C1=O
PubChem CID 145712377
Molecular Weight 569.47

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 17.86 mg/mL (31.36 mM; Need ultrasonic)

Related Documents

Solution Calculators