MeCP2 Mouse mAb - Primary antibody, specific to MECP2, Mouse IgG1

Features and benefits
  • Short Overview:

    mAb (C7); Mouse anti Human MeCP2 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Mouse IgG1
    Application:
  • WB
Item Number
Ab114749
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab114749-10μl
10μl
In stock
$66.90
Ab114749-20μl
20μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
Ab114749-50μl
50μl
In stock
$199.90
Ab114749-100μl
100μl
In stock
$319.90
Ab114749-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

mAb (C7); Mouse anti Human MeCP2 Antibody; WB; Unconjugated

Basic Description

Product NameMeCP2 Mouse mAb - Primary antibody, specific to MECP2, Mouse IgG1
SynonymsAUTSX 3 antibody; AUTSX3 antibody; DKFZp686A24160 antibody; Mbd 5 antibody; Mbd5 antibody; MECP 2 antibody; MeCP 2 protein antibody; MeCP-2 protein antibody; Mecp2 antibody; MECP2_HUMAN antibody; Methyl CpG binding protein 2 (Rett syndrome) antibody; Meth
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot
Host speciesMouse
SpecificityMECP2
ImmunogenRecombinant MECP2 expressed in E.coli (AA 1-177).
Positive ControlWB: SK-N-SH, NIH/3T3 and C6 cell lysates.
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human MeCP2 Antibody, Monoclonal (C7), could be used for WB and so on.
Application:
WB: 0.5-2µg/mL
Protein Function
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A.
Post-translational
Phosphorylated on Ser-423 in brain upon synaptic activity, which attenuates its repressor activity and seems to regulate dendritic growth and spine maturation.

Product Properties

IsotypeMouse IgG1
SDS-PAGE150 kDa
Purification MethodProtein A + Protein G purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 2-8°C short term (2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

MeCP2 Mouse mAb (Ab114749) - Western Blot
All lanes: MeCP2 Mouse mAb (Ab114749) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 52 kDa
Observed band size: 81 kDa
Exposure time: 60.0 s

MeCP2 Mouse mAb (Ab114749) - Western Blot
All lanes: MeCP2 Mouse mAb (Ab114749) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 52 kDa
Observed band size: 51 kDa
Exposure time: 52.9 s

Associated Targets(Human)

MECP2 Tchem Methyl-CpG-binding protein 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Methyl-CpG-binding protein 2 12 Activities

Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Application

ApplicationDilution info
WB

0.5-2 µg/mL

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404480Certificate of AnalysisApr 12, 2024 Ab114749
ZJ24F0404479Certificate of AnalysisApr 12, 2024 Ab114749
ZJ24F0404478Certificate of AnalysisApr 12, 2024 Ab114749

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