Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M303878-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $66.90 | |
M303878-250mg | 250mg | In stock | $71.90 | |
M303878-1g | 1g | In stock | $236.90 | |
M303878-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,066.90 |
Synonyms | Medroxyprogesteron | Opera_ID_433 | 17-Hydroxy-6a-methylprogesterone | medroxyprogesterone | (6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione | C07119 | Medroxy Progesterone | Medroxyprogesteronum (INN-Latin) | MLS000069571 | Tox21_113401 | MEDROXYPROGE |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Room temperature,Desiccated |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of Progesterone receptor |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one |
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INCHI | InChI=1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1 |
InChi Key | FRQMUZJSZHZSGN-HBNHAYAOSA-N |
Canonical SMILES | CC1CC2C(CCC3(C2CCC3(C(=O)C)O)C)C4(C1=CC(=O)CC4)C |
Isomeric SMILES | C[C@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)O)C)[C@@]4(C1=CC(=O)CC4)C |
PubChem CID | 10631 |
Molecular Weight | 344.5 |
DrugBank Ligand | DB00603 |
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PubChem CID | 10631 |
Wikipedia | Medroxyprogesterone |
CAS Registry No. | 520-85-4 |
ChEMBL Ligand | CHEMBL1390 |
ChEBI | CHEBI:6715 |
PEP | medroxyprogesterone |
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Solubility | Insoluble in water; Degree of Solubility in water: 2.95 mg/l 25 °C; Very soluble in Chloroform |
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Specific Rotation[α] | 75° (C=1,CHCl3) |
Melt Point(°C) | 217 °C |
Pictogram(s) | GHS08 |
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Signal | Warning |
Hazard Statements | H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
Merck Index | 5793 |
1. Min Liu, Yong-Jie Mi, Juan Dai. (2023) Aquaporin 7 is upregulated through the PI3K-Akt pathway and modulates decidualisation of endometrial stromal cells. REPRODUCTION FERTILITY AND DEVELOPMENT, 35 (14): (669-675). [PMID:37879294] [10.1071/RD23054] |
2. Xiaomei Chen, Liulin Wei, Qian Liu, Xueyun Gao, Jingchan Zhao. (2023) Application of temperature-sensitive hyperbranched polysiloxanes for the determination of polycyclic aromatic hydrocarbons in foodstuffs. MICROCHEMICAL JOURNAL, 194 (14): (109364). [PMID:19683501] [10.1016/j.microc.2023.109364] |
1. Min Liu, Yong-Jie Mi, Juan Dai. (2023) Aquaporin 7 is upregulated through the PI3K-Akt pathway and modulates decidualisation of endometrial stromal cells. REPRODUCTION FERTILITY AND DEVELOPMENT, 35 (14): (669-675). [PMID:37879294] [10.1071/RD23054] |
2. Xiaomei Chen, Liulin Wei, Qian Liu, Xueyun Gao, Jingchan Zhao. (2023) Application of temperature-sensitive hyperbranched polysiloxanes for the determination of polycyclic aromatic hydrocarbons in foodstuffs. MICROCHEMICAL JOURNAL, 194 (14): (109364). [PMID:19683501] [10.1016/j.microc.2023.109364] |