Skip to the beginning of the images gallery

MEL57A , CAS No.M611782, Channel blocker of HCN1;Channel blocker of HCN2;Channel blocker of HCN4

Moligand™

≥95%

CAS#: 1245568-07-3
Formula: C₄₃H₅₁N₃O₈
Molecular Weight: 737.88

Item Number

M611782

Grouped product items
SKU	Size	Availability	Price
M611782-5mg	5mg	In stock	$1,300.90
M611782-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,999.90
M611782-25mg	25mg	In stock	$2,999.90

View related series

HCN1 Channel blocker HCN2 Channel blocker HCN4 Channel blocker

Basic Description

Synonyms	(R) N,N-bis-[ (Z)-4-(7,8-dimethoxy-2- oxo-1,3-dihydrobenzo[d]azepin-3-yl)but-2-enyl]-2-(3,4- dimethoxyphenyl)-propanamine
Specifications & Purity	Moligand™, ≥95%
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of HCN1;Channel blocker of HCN2;Channel blocker of HCN4

Associated Targets(Human)

HCN1 Tclin Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (1 Activities)

Discover Target: HCN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HCN2 Tclin Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (0 Activities)

Discover Target: HCN2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HCN4 Tclin Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (0 Activities)

Discover Target: HCN4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Associated Targets(non-human)

Hcn1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (22 Activities)

Discover Target: Hcn1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hcn2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (15 Activities)

Discover Target: Hcn2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ChEMBL Ligand

CHEMBL1253475

PubChem CID

46937420

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
K2418361	Certificate of Analysis	Nov 15, 2024	M611782
K2418362	Certificate of Analysis	Nov 15, 2024	M611782
K2418363	Certificate of Analysis	Nov 15, 2024	M611782
K2418364	Certificate of Analysis	Nov 15, 2024	M611782
K2418365	Certificate of Analysis	Nov 15, 2024	M611782
K2418366	Certificate of Analysis	Nov 15, 2024	M611782

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

MEL57A , CAS No.M611782, Channel blocker of HCN1;Channel blocker of HCN2;Channel blocker of HCN4

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator