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Meleagrin - ≥98%, high purity , CAS No.71751-77-4
an alkaloid displaying antineoplastic activity
Basic Description
Synonyms | (3E,7AR,12AS)-7A-(1,1-DIMETHYL-2-PROPEN-1-YL)-7A,12-DIHYDRO-6-HYDROXY-3-(1H-IMIDAZOL-5-YLMETHYLENE)-12-METHOXY-1H,5H-IMIDAZO(1',2':1,2)PYRIDO(2,3-B)INDOLE-2,5(3H)-DIONE | HY-N6797 | BCP14992 | DTXSID80891812 | 1H,5H-IMIDAZO(1',2':1,2)PYRIDO(2,3-B)INDOLE-2 |
Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Meleagrin is an alkaloid antibiotic that is mainly isolated from|Penicillium|species. Meleagrin has shown some cell ctyotoxicity. |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
IUPAC Name | (1S,9R,14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7,10-tetraene-12,15-dione |
INCHI | InChI=1S/C23H23N5O4/c1-5-21(2,3)22-11-18(29)20(31)27-17(10-14-12-24-13-25-14)19(30)26-23(22,27)28(32-4)16-9-7-6-8-15(16)22/h5-13,29H,1H2,2-4H3,(H,24,25)(H,26,30)/b17-10+/t22-,23-/m0/s1 |
InChi Key | JTJJJLSLKZFEPJ-ZAYCRUKZSA-N |
Canonical SMILES | CC(C)(C=C)C12C=C(C(=O)N3C1(NC(=O)C3=CC4=CN=CN4)N(C5=CC=CC=C25)OC)O |
Isomeric SMILES | CC(C)(C=C)[C@@]12C=C(C(=O)N\3[C@]1(NC(=O)/C3=C\C4=CN=CN4)N(C5=CC=CC=C25)OC)O |
PubChem CID | 23728435 |
Molecular Weight | 433.46 |
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Chemical and Physical Properties
Solubility | Soluble in 100% ethanol, and DMSO. |
Refractive Index | n20D1.72 (Predicted) |
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