Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M129228-5g | 5g | In stock | $46.90 | |
M129228-10g | 10g | In stock | $83.90 | |
M129228-25g | 25g | In stock | $136.90 | |
M129228-100g | 100g | In stock | $492.90 |
Nonsteroidal anti-inflammatory drug (NSAID)
Synonyms | UH-AC 62XX | Meloxicam (JAN/USP/INN) | Meloxoral | MLS006011422 | QMIIZ ODT | AMOXICILLIN CRYSTALLINE | C14H13N3O4S2 | MELOXICAM [EP MONOGRAPH] | Meloxicam Solution for Injection | VG2QF83CGL | Vivlodex | BIDD:GT0726 | Emdocam | Movatec | Parocin | Metaca |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Meloxicam, a non-steroidal anti-inflammatory agent, has been reported to inhibit the inducible isoform of Cox-2. Meloxicam is an inhibitor selective for Cox-2 (IC50 of 4.7 μM) over Cox-1 (IC50 of 36.6 μM). Studies suggest that Meloxicam is Cox-2 preferent |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of COX-1;Inhibitor of COX-2 |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide |
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INCHI | InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19) |
InChi Key | ZRVUJXDFFKFLMG-UHFFFAOYSA-N |
Canonical SMILES | CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O |
Isomeric SMILES | CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O |
RTECS | DL0702000 |
PubChem CID | 54677470 |
UN Number | 2811 |
Packing Group | III |
Molecular Weight | 351.4 |
Reaxy-Rn | 5886369 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
D2422191 | Certificate of Analysis | Mar 26, 2024 | M129228 |
D2422192 | Certificate of Analysis | Mar 26, 2024 | M129228 |
G1515087 | Certificate of Analysis | May 09, 2023 | M129228 |
D2117281 | Certificate of Analysis | Feb 08, 2023 | M129228 |
D2117285 | Certificate of Analysis | Feb 08, 2023 | M129228 |
K2217942 | Certificate of Analysis | Oct 31, 2022 | M129228 |
K2217985 | Certificate of Analysis | Oct 31, 2022 | M129228 |
K2217986 | Certificate of Analysis | Oct 31, 2022 | M129228 |
K2217988 | Certificate of Analysis | Oct 31, 2022 | M129228 |
Solubility | H2O: 0.67 mg/mL (1.91 mM; ultrasound assisted dissolution); DMSO: 25 mg/mL (71.14 mM; ultrasound assisted dissolution (<60 ° C); Ethanol:<1 mg/mL |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 255°C |
Pictogram(s) | GHS06, GHS08 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed H412:Harmful to aquatic life with long lasting effects H360:May damage fertility or the unborn child |
Precautionary Statements | P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. |
RTECS | DL0702000 |
Reaxy-Rn | 5886369 |
Class | 6.1 |
Merck Index | 5826 |
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1. Gilbert Audira, Jong-Chin Huang, Kelvin H.-C. Chen, Kevin Adi Kurnia, Ross D. Vasquez, Marri Jmelou M. Roldan, Yu-Heng Lai, Chung-Der Hsiao, Cheng-Yo Yen. (2023) A comprehensive painkillers screening by assessing zebrafish behaviors after caudal fin amputation. BIOMEDICINE & PHARMACOTHERAPY, 168 (115641). [PMID:37806085] |
2. Zhong-Xia Wang, Kai-Qi Liu, Xiang-Ying Meng, Feng Li, Heng-Ye Li, Hang Gao, Wei Wang. (2023) An eco-friendly fluorometric assay for high-sensitive meloxicam quantitation in biological matrices. ANALYST, 148 (18): (4339-4345). [PMID:37580992] |
3. Meizhu Qin, Xinping Hu, Jingyan Guo. (2023) Preparation of a New Type of Expansion Flame Retardant and Application in Polystyrene. Coatings, 13 (4): (733). [PMID:] |
4. Jiana Lin, Xiaoyan Ouyang, Yuling Hu, Gongke Li, Qisheng Zhong. (2023) Primary amide-functionalized cyclotricatechylene covalent organic frameworks membrane for efficient enrichment of melamine and its derivatives in migration solution of food contact materials. JOURNAL OF SEPARATION SCIENCE, 46 (6): (202200862). [PMID:36680331] |
5. Chenghua Song, Ruichao Wen, Jiaxuan Zhou, Xiaoyan Zeng, Zi Kou, Yufeng Li, Feng Yun, Rongqian Wu. (2022) UV C Light from a Light-Emitting Diode at 275 Nanometers Shortens Wound Healing Time in Bacterium- and Fungus-Infected Skin in Mice. Microbiology Spectrum, [PMID:36453911] |
6. Chenghua Song, Ruichao Wen, Jiaxuan Zhou, Xiaoyan Zeng, Zi Kou, Jia Zhang, Tao Wang, Pengkang Chang, Yi Lv, Rongqian Wu. (2022) Antibacterial and Antifungal Properties of a Novel Antimicrobial Peptide GK-19 and Its Application in Skin and Soft Tissue Infections Induced by MRSA or Candida albicans. Pharmaceutics, 14 (9): (1937). [PMID:36145681] |
7. Xiaochun Hu, Yuqing Luo, Xianyue Wu, Jiabin Niu, Mingwu Tan, Zhiqiang Sun, Wen Liu. (2022) Heteroatom-doped microporous carbon nanosheets derived from pentaerythritol-melamine for supercapacitors and CO2 capture. Materials Today Energy, 27 (101010). [PMID:] |
8. Ya Xu, Ru Zhou, Jingjing Mu, Yanming Ding, Juncheng Jiang. (2022) Synergistic flame retardancy of linear low-density polyethylene with surface modified intumescent flame retardant and zinc borate. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 640 (128400). [PMID:] |
1. Gilbert Audira, Jong-Chin Huang, Kelvin H.-C. Chen, Kevin Adi Kurnia, Ross D. Vasquez, Marri Jmelou M. Roldan, Yu-Heng Lai, Chung-Der Hsiao, Cheng-Yo Yen. (2023) A comprehensive painkillers screening by assessing zebrafish behaviors after caudal fin amputation. BIOMEDICINE & PHARMACOTHERAPY, 168 (115641). [PMID:37806085] |
2. Zhong-Xia Wang, Kai-Qi Liu, Xiang-Ying Meng, Feng Li, Heng-Ye Li, Hang Gao, Wei Wang. (2023) An eco-friendly fluorometric assay for high-sensitive meloxicam quantitation in biological matrices. ANALYST, 148 (18): (4339-4345). [PMID:37580992] |
3. Meizhu Qin, Xinping Hu, Jingyan Guo. (2023) Preparation of a New Type of Expansion Flame Retardant and Application in Polystyrene. Coatings, 13 (4): (733). [PMID:] |
4. Jiana Lin, Xiaoyan Ouyang, Yuling Hu, Gongke Li, Qisheng Zhong. (2023) Primary amide-functionalized cyclotricatechylene covalent organic frameworks membrane for efficient enrichment of melamine and its derivatives in migration solution of food contact materials. JOURNAL OF SEPARATION SCIENCE, 46 (6): (202200862). [PMID:36680331] |
5. Chenghua Song, Ruichao Wen, Jiaxuan Zhou, Xiaoyan Zeng, Zi Kou, Yufeng Li, Feng Yun, Rongqian Wu. (2022) UV C Light from a Light-Emitting Diode at 275 Nanometers Shortens Wound Healing Time in Bacterium- and Fungus-Infected Skin in Mice. Microbiology Spectrum, [PMID:36453911] |
6. Chenghua Song, Ruichao Wen, Jiaxuan Zhou, Xiaoyan Zeng, Zi Kou, Jia Zhang, Tao Wang, Pengkang Chang, Yi Lv, Rongqian Wu. (2022) Antibacterial and Antifungal Properties of a Novel Antimicrobial Peptide GK-19 and Its Application in Skin and Soft Tissue Infections Induced by MRSA or Candida albicans. Pharmaceutics, 14 (9): (1937). [PMID:36145681] |
7. Xiaochun Hu, Yuqing Luo, Xianyue Wu, Jiabin Niu, Mingwu Tan, Zhiqiang Sun, Wen Liu. (2022) Heteroatom-doped microporous carbon nanosheets derived from pentaerythritol-melamine for supercapacitors and CO2 capture. Materials Today Energy, 27 (101010). [PMID:] |
8. Ya Xu, Ru Zhou, Jingjing Mu, Yanming Ding, Juncheng Jiang. (2022) Synergistic flame retardancy of linear low-density polyethylene with surface modified intumescent flame retardant and zinc borate. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 640 (128400). [PMID:] |