Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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M191037-250mg | 250mg | In stock | $175.90 | |
M191037-1g | 1g | In stock | $525.90 | |
M191037-5g | 5g | In stock | $1,749.90 |
Alkylating agent. Phenylamine derivative of mechorethamine
Synonyms | melphalan | 148-82-3 | Alkeran | Melfalan | L-PAM | Phenylalanine mustard | L-Sarcolysine | L-Phenylalanine mustard | L-Sarcolysin | p-L-Sarcolysin | Levofalan | Levofolan | Levopholan | Melfalano | Melphalanum | L-Sarkolysin | Phenylalanine nitrogen mustard | 4-[Bis(2-chloroethyl)amino]- |
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Specifications & Purity | Moligand™, ≥90% |
Biochemical and Physiological Mechanisms | Alkylating agent. Phenylamine derivative of mechorethamine. Attaches an alkyl group to the guanine base of DNA at the number 7 nitrogen atom of the imidazole ring. Active in vivo . |
Storage Temp | Room temperature |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | DNA inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Melphalan is an effective DNA alkylating agent, with potent antitumor activity. |
ALogP | -0.5 |
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Pubchem Sid | 488189913 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488189913 |
IUPAC Name | (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid |
INCHI | InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1 |
InChi Key | SGDBTWWWUNNDEQ-LBPRGKRZSA-N |
Canonical SMILES | C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl |
Isomeric SMILES | C1=CC(=CC=C1C[C@@H](C(=O)O)N)N(CCCl)CCCl |
PubChem CID | 460612 |
UN Number | 2811 |
Packing Group | I |
Molecular Weight | 305.2 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
I2118376 | Certificate of Analysis | Jul 04, 2024 | M191037 |
B23021140 | Certificate of Analysis | Nov 23, 2022 | M191037 |
B23021165 | Certificate of Analysis | Nov 23, 2022 | M191037 |
B23021168 | Certificate of Analysis | Nov 23, 2022 | M191037 |
B23021170 | Certificate of Analysis | Nov 23, 2022 | M191037 |
B2303008 | Certificate of Analysis | Nov 23, 2022 | M191037 |
B2303024 | Certificate of Analysis | Nov 23, 2022 | M191037 |
H2205595 | Certificate of Analysis | Jun 18, 2022 | M191037 |
H2205596 | Certificate of Analysis | Jun 18, 2022 | M191037 |
C1906056 | Certificate of Analysis | Jan 22, 2022 | M191037 |
A2214609 | Certificate of Analysis | Dec 10, 2021 | M191037 |
A2214610 | Certificate of Analysis | Dec 10, 2021 | M191037 |
A2214611 | Certificate of Analysis | Dec 10, 2021 | M191037 |
Pictogram(s) | GHS06, GHS08 |
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Signal | Danger |
Hazard Statements | H300:Fatal if swallowed H310:Fatal in contact with skin H330:Fatal if inhaled H350:May cause cancer H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. P316:Get emergency medical help immediately. |
Class | 6.1 |