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Menadione - meets USP testing specifications, high purity , CAS No.58-27-5

  • PharmPure™
  • USP
Item Number
M432985
Grouped product items
SKUSizeAvailabilityPrice Qty
M432985-25g
25g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$106.90
M432985-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$429.90

Basic Description

Synonymsmenadione|58-27-5|Vitamin K3|2-Methyl-1,4-naphthoquinone|2-methylnaphthalene-1,4-dione|Menaphthone|Kayquinone|2-Methylnaphthoquinone|Thyloquinone|Kappaxin|Kayklot|Klottone|Kolklot|Panosine|Kanone|2-Methyl-1,4-naphthalenedione|Menadion|Menaphthon|Kipca|Pro
Specifications & Puritymeets USP testing specifications
GradePharmPure™, USP
Product Description

Gene Information

human ... NQO1(1728)


Menadione (Vitamin K3) is the synthetic form of vitamin K. It has the structure similar to vitamin K1 and K2. Vitamin K1, K2 and K3 are biologically active. Water soluble forms of menadiones are used in swine and poultry diets.


Application

Menadione has been used: to treat HL-60 cells as positive control for apoptosis for flow cytometry as an oxidative stress inducer in transgenic embryos after 24 h of post fertilization to treat HaCaT cell line, for quantifying total and oxidised glutathione

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TST Tchem Thiosulfate sulfurtransferase 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOB Tclin Amine oxidase [flavin-containing] B 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AOX1 Tchem Aldehyde oxidase 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDO1 Tchem Indoleamine 2,3-dioxygenase 1 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-methylnaphthalene-1,4-dione
INCHI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
InChi Key MJVAVZPDRWSRRC-UHFFFAOYSA-N
Canonical SMILES CC1=CC(=O)C2=CC=CC=C2C1=O
Isomeric SMILES CC1=CC(=O)C2=CC=CC=C2C1=O
WGK Germany 3
RTECS QL9100000
PubChem CID 4055
UN Number 1325
Molecular Weight 172.18
Beilstein 1908453

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Melt Point(°C)105-108°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H341:Suspected of causing genetic defects

H302:Harmful if swallowed

H317:May cause an allergic skin reaction

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS QL9100000
Merck Index 5831

Related Documents

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