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meso-2,6-Diaminopimelic acid - ≥98% (TLC), high purity , CAS No.922-54-3, Agonist of nucleotide binding oligomerization domain containing 1

  • Moligand™
Item Number
M465023
Grouped product items
SKUSizeAvailabilityPrice Qty
M465023-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$699.90
M465023-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,730.90

Basic Description

Synonyms(2R,6S)-2,6-diaminoheptanedioic acid|922-54-3|meso-DAP|meso-2,6-Diaminopimelic acid|V5KRL7N7GD|1356383-43-1|Diaminopimelic acid, meso-|(2S,6R)-2,6-diaminoheptanedioic acid|meso-diaminoheptanedioic acid|(R*,S*)-2,6-Diaminoheptanedioic acid|meso-diaminohept
Specifications & Purity≥98% (TLC)
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of nucleotide binding oligomerization domain containing 1
Product Description

Description

Meso-2,6-diaminopimelic acid may be used to study peptidoglycan structure and function within the cell walls of bacteria.

Associated Targets

NOD1 Tchem Nucleotide-binding oligomerization domain-containing protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S,6R)-2,6-diaminoheptanedioic acid
INCHI InChI=1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5+
InChi Key GMKMEZVLHJARHF-SYDPRGILSA-N
Canonical SMILES C(CC(C(=O)O)N)CC(C(=O)O)N
Isomeric SMILES C(C[C@H](C(=O)O)N)C[C@@H](C(=O)O)N
PubChem CID 99290
Molecular Weight 190.2
Beilstein 1726899

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Flash Point(°F)Not applicable
Flash Point(°C)Not applicable

Safety and Hazards(GHS)

Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

RIDADR NONH for all modes of transport

Related Documents

References

1. J McKerrow,S Vagg,T McKinney,E M Seviour,A M Maszenan,P Brooks,R J Seviour.  (2000-04-04)  A simple HPLC method for analysing diaminopimelic acid diastereomers in cell walls of Gram-positive bacteria..  Letters in applied microbiology,  30  ((3)): (178-182).  [PMID:10747246]
2. S Satyanarayana,J S Grossert,S F Lee,R L White.  (2002-01-05)  Determination of diamino acids in peptidoglycans from anaerobic bacteria..  Amino acids,  21  ((3)): (221-235).  [PMID:11764403]
3. Yukari Fujimoto,Katsunori Tanaka,Atsushi Shimoyama,Koichi Fukase.  (2010-09-08)  Self and nonself recognition with bacterial and animal glycans, surveys by synthetic chemistry..  Methods in enzymology,  478  (323-342).  [PMID:20816488]
4. A Day,P J White.  (1977-03-01)  Enzymic assays for isomers of 2,6-diaminopimelic acid in walls of Bacillus cereus and Bacillus megaterium..  The Biochemical journal,  161  ((3)): (677-685).  [PMID:403912]
5. N V Potekhina,I B Naumova,A S Shashkov,L P Terekhova.  (1991-07-15)  Structural features of cell wall teichoic acid and peptidoglycan of Actinomadura cremea INA 292..  European journal of biochemistry,  199  ((2)): (313-316).  [PMID:2070791]
6. Luigi Franchi,Jong-Hwan Park,Michael H Shaw,Noemi Marina-Garcia,Grace Chen,Yun-Gi Kim,Gabriel Núñez.  (2007-10-20)  Intracellular NOD-like receptors in innate immunity, infection and disease..  Cellular microbiology,  10  ((1)): (1-8).  [PMID:17944960]
7. Simon J Ittig,Christoph Schmutz,Christoph A Kasper,Marlise Amstutz,Alexander Schmidt,Loïc Sauteur,M Alessandra Vigano,Shyan Huey Low,Markus Affolter,Guy R Cornelis,Erich A Nigg,Cécile Arrieumerlou.  (2015-11-26)  A bacterial type III secretion-based protein delivery tool for broad applications in cell biology..  The Journal of cell biology,  211  ((4)): (913-931).  [PMID:26598622]

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