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meso-2,6-Diaminopimelic acid - ≥98% (TLC), high purity , CAS No.922-54-3, Agonist of nucleotide binding oligomerization domain containing 1

Moligand™

≥98%(TLC)

CAS#: 922-54-3
Formula: C₇H₁₄N₂O₄
Molecular Weight: 190.2
Beilstein Registry Number: 1726899
MDL number: MFCD09836095
PubChem CID: 99290

Item Number

M465023

Grouped product items
SKU	Size	Availability	Price	Qty
M465023-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$699.90
M465023-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,730.90

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nucleotide binding oligomerization domain containing 1 Agonist

Basic Description

Synonyms	AKOS006328542 \| C00680 \| Heptanedioic acid, 2,6-diamino-, meso- (8CI) \| meso-2,6-diaminoheptanedioate \| meso-1-alpha,epsilon-diaminopimelate \| meso-2,6-Diaminopimelate \| NSC-206289 \| Q209275 \| .ALPHA.,.EPSILON.-DIAMINOPIMELIC ACID \| meso-2,6-Diaminopimeli
Specifications & Purity	Moligand™, ≥98%(TLC)
Biochemical and Physiological Mechanisms	Penultimate biosynthetic precursor of the essential amino acid L-lysine. Component of peptidoglycan in the cell wall of many bacteria.
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of nucleotide binding oligomerization domain containing 1
Product Description	Description Meso-2,6-diaminopimelic acid may be used to study peptidoglycan structure and function within the cell walls of bacteria.

Names and Identifiers

IUPAC Name	(2S,6R)-2,6-diaminoheptanedioic acid
INCHI	InChI=1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5+
InChi Key	GMKMEZVLHJARHF-SYDPRGILSA-N
Canonical SMILES	C(CC(C(=O)O)N)CC(C(=O)O)N
Isomeric SMILES	C(C[C@H](C(=O)O)N)C[C@@H](C(=O)O)N
PubChem CID	99290
Molecular Weight	190.2
Beilstein	1726899

Wikipedia

ChEBI

PubChem CID

CAS Registry No.

ChEMBL Ligand

RCSB PDB Ligand

Flash Point(°F)

Not applicable

Flash Point(°C)

Not applicable

Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
RIDADR	NONH for all modes of transport

References

1. J McKerrow,S Vagg,T McKinney,E M Seviour,A M Maszenan,P Brooks,R J Seviour. (2000-04-04) A simple HPLC method for analysing diaminopimelic acid diastereomers in cell walls of Gram-positive bacteria.. Letters in applied microbiology, 30 ((3)): (178-182). [PMID:10747246]
2. S Satyanarayana,J S Grossert,S F Lee,R L White. (2002-01-05) Determination of diamino acids in peptidoglycans from anaerobic bacteria.. Amino acids, 21 ((3)): (221-235). [PMID:11764403]
3. Yukari Fujimoto,Katsunori Tanaka,Atsushi Shimoyama,Koichi Fukase. (2010-09-08) Self and nonself recognition with bacterial and animal glycans, surveys by synthetic chemistry.. Methods in enzymology, 478 (323-342). [PMID:20816488]
4. A Day,P J White. (1977-03-01) Enzymic assays for isomers of 2,6-diaminopimelic acid in walls of Bacillus cereus and Bacillus megaterium.. The Biochemical journal, 161 ((3)): (677-685). [PMID:403912]
5. N V Potekhina,I B Naumova,A S Shashkov,L P Terekhova. (1991-07-15) Structural features of cell wall teichoic acid and peptidoglycan of Actinomadura cremea INA 292.. European journal of biochemistry, 199 ((2)): (313-316). [PMID:2070791]
6. Luigi Franchi,Jong-Hwan Park,Michael H Shaw,Noemi Marina-Garcia,Grace Chen,Yun-Gi Kim,Gabriel Núñez. (2007-10-20) Intracellular NOD-like receptors in innate immunity, infection and disease.. Cellular microbiology, 10 ((1)): (1-8). [PMID:17944960]
7. Simon J Ittig,Christoph Schmutz,Christoph A Kasper,Marlise Amstutz,Alexander Schmidt,Loïc Sauteur,M Alessandra Vigano,Shyan Huey Low,Markus Affolter,Guy R Cornelis,Erich A Nigg,Cécile Arrieumerlou. (2015-11-26) A bacterial type III secretion-based protein delivery tool for broad applications in cell biology.. The Journal of cell biology, 211 ((4)): (913-931). [PMID:26598622]

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meso-2,6-Diaminopimelic acid - ≥98% (TLC), high purity , CAS No.922-54-3, Agonist of nucleotide binding oligomerization domain containing 1

Basic Description

Associated Targets(Human)

Mechanisms of Action

Names and Identifiers

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Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

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References

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