Mesopram - ≥98%(HPLC), high purity , CAS No.189940-24-7

  • ≥98%(HPLC)
Item Number
M288757
Grouped product items
SKUSizeAvailabilityPrice Qty
M288757-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$159.90
M288757-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$627.90

PDE5 inhibitor

Basic Description

SynonymsBDBM50308512 | AKOS024457404 | SCHEMBL450823 | SH636 | SH-636 | [R]-Mesopram | (5R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-1,3-oxazolidin-2-one | (R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone | Daxalipram | DAXALIPRAM [WHO-DD] | ZK 117137 | 2
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsOrally active phosphodiesterase (PDE) 4 inhibitor. Inhibits Th1 cell proliferation and decreases production of IFN-γ, TNF-α, IL-10 and iNOSin vitro. Triggers ovulation and exhibits efficacy against experimental autoimmune encephalomyelitis and murine coli
Storage TempStore at 2-8°C
Shipped InWet ice

Associated Targets(Human)

PDE4B Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4B (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE4B Tclin Phosphodiesterase 4B (2748 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (5R)-5-(4-methoxy-3-propoxyphenyl)-5-methyl-1,3-oxazolidin-2-one
INCHI InChI=1S/C14H19NO4/c1-4-7-18-12-8-10(5-6-11(12)17-3)14(2)9-15-13(16)19-14/h5-6,8H,4,7,9H2,1-3H3,(H,15,16)/t14-/m0/s1
InChi Key PCCPERGCFKIYIS-AWEZNQCLSA-N
Canonical SMILES CCCOC1=C(C=CC(=C1)C2(CNC(=O)O2)C)OC
Isomeric SMILES CCCOC1=C(C=CC(=C1)[C@@]2(CNC(=O)O2)C)OC
PubChem CID 449190
Molecular Weight 265.31

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 26.53, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 26.53, Max Conc. mM: 100

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Solution Calculators