Methimepip dihydrobromide - ≥98%, high purity , CAS No.151070-80-3, Agonist of H 3 receptor;Agonist of H 4 receptor

Item Number

M347550

Grouped product items
SKU	Size	Availability	Price	Qty
M347550-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$147.90
M347550-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$636.90

a selective histamine H3 receptor agonist

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Basic Description

Synonyms	AKOS040756007 \| J-008778 \| Methimepip (hydrobromide) \| 4-(1H-imidazol-5-ylmethyl)-1-methylpiperidine;dihydrobromide \| 4-((1H-imidazol-4-yl)methyl)-1-methylpiperidine dihydrobromide \| Methimepip dihydrobromide \| DTXSID80462102 \| AKOS024457350 \| PD079525 \|
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Room temperature,Desiccated
Shipped In	Normal
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of H 3 receptor;Agonist of H 4 receptor
Product Description	Methimepip dihydrobromide extremely selective histamine H3 receptor agonist [pKi values are 9.0, 5.7, < 5.0 and < 5.0 for Histamine H3 (hH3), Histamine H4 (hH4), Histamine H1(hH1) and Histamine H2(hH2) receptors respectively]. Potently inhibits EFS-evoked contractions of guinea pig ileum (pD2 = 8.26).

Associated Targets(Human)

HRH4 Tchem Histamine H4 receptor (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HRH3 Tclin Histamine H3 receptor (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	4-(1H-imidazol-5-ylmethyl)-1-methylpiperidine;dihydrobromide
INCHI	InChI=1S/C10H17N3.2BrH/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10;;/h7-9H,2-6H2,1H3,(H,11,12);2*1H
InChi Key	XTJPHXJFOFOXJG-UHFFFAOYSA-N
Canonical SMILES	CN1CCC(CC1)CC2=CN=CN2.Br.Br
Isomeric SMILES	CN1CCC(CC1)CC2=CN=CN2.Br.Br
PubChem CID	11313836
Molecular Weight	179.26