Methyl indole-3-carboxylate - 99%, high purity , CAS No.942-24-5

  • ≥99%
Item Number
M103561
Grouped product items
SKUSizeAvailabilityPrice Qty
M103561-5g
5g
In stock
$9.90
M103561-25g
25g
In stock
$29.90
M103561-100g
100g
In stock
$106.90
M103561-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$319.90

Basic Description

SynonymsDTXSID10343334 | Indole-3-carboxylic Acid Methyl Ester | Methyl 1H-indole-3-carboxylate # | methylindole-3-carboxylate | Indole-3-carboxylic acid methyl ester, 99% | METHYL INDOLE-3- CARBOXYLATE | HY-79635 | SY020043 | Z57164966 | InChI=1/C10H9NO2/c1-13-1
Specifications & Purity≥99%
Shipped InNormal
Product Description

Usually uesed as reactant for preparation of Nitric oxide synthase (nNOS) inhibitorS,Protein kinase c alpha (PKCα) inhibitors,Organocatalysts for the anti-Mannich reaction,Inhibitors of Human 5-Lipoxygenase,Hyaluronidase inhibitors.


product description:

Methyl indole-3-carboxylate (3-Methoxycarbonylindole, 3-Carbomethoxyindole, Methyl indolyl-3-carboxylate) has been extracted from the marine Streptomyces sp. 060524. Its crystal structure indicates the presence of inter¬molecular N-H…O hydrogen bond. It is also obtained during the isolation of sorazinones A and B from Sorangium cellulosum strain Soce895. It undergoes regioselective dibromination with bromine in acetic acid to afford methyl 5,6-dibromoindole-3-carboxylate.

Associated Targets(Human)

TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR4A2 Tchem Nuclear receptor subfamily 4 group A member 2 (460 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CREBBP Tchem CREB-binding protein (1602 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BRD4 Tchem Bromodomain-containing protein 4 (13122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L929 (3802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Chromobacterium violaceum (349 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mucor hiemalis (184 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycolicibacterium diernhoferi (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nocardia sp. (39 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Wickerhamomyces anomalus (305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryphonectria parasitica (24 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Paenibacillus polymyxa (51 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488190497
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488190497
IUPAC Name methyl 1H-indole-3-carboxylate
INCHI InChI=1S/C10H9NO2/c1-13-10(12)8-6-11-9-5-3-2-4-7(8)9/h2-6,11H,1H3
InChi Key QXAUTQFAWKKNLM-UHFFFAOYSA-N
Canonical SMILES COC(=O)C1=CNC2=CC=CC=C21
Isomeric SMILES COC(=O)C1=CNC2=CC=CC=C21
WGK Germany 3
PubChem CID 589098
Molecular Weight 175.18
Beilstein 22,65
Reaxy-Rn 142023

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
E1611136Certificate of AnalysisJan 17, 2024 M103561
C1810003Certificate of AnalysisJan 20, 2022 M103561

Chemical and Physical Properties

SolubilitySlightly soluble methanol and dimethyl sulfoxide. Insoluble in water.
Melt Point(°C)149-152°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 142023

Related Documents

Citations of This Product

1. Xiang Xu, Yi Shen, Yue Shu, Yong Guan, Dafu Wei.  (2022)  Synthesis and application of poly methyl indole-4-carboxylate with blue light blocking properties.  EUROPEAN POLYMER JOURNAL,  171  (111198).  [PMID:]

References

1. Xiang Xu, Yi Shen, Yue Shu, Yong Guan, Dafu Wei.  (2022)  Synthesis and application of poly methyl indole-4-carboxylate with blue light blocking properties.  EUROPEAN POLYMER JOURNAL,  171  (111198).  [PMID:]

Solution Calculators