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SKU

Size

Availability

Price

Qty

M134389-1g

In stock

$9.90

M134389-5g

Available within 1-2 weeks(?)

$13.90

M134389-25g

25g

Available within 1-2 weeks(?)

$23.90

M134389-100g

100g

In stock

$85.90

M134389-500g

500g

Available within 4-8 weeks(?)

$384.90

Basic Description

Synonyms	methylene blue\|61-73-4\|Basic blue 9\|Methylthioninium chloride\|Solvent blue 8\|Swiss Blue\|Chromosmon\|Methylene Blue anhydrous\|Methylene Blue N\|Methylene Blue BB\|Methylenium ceruleum\|C.I. Basic Blue 9\|Urolene blue\|3,7-Bis(dimethylamino)phenothiazin-5-ium chl
Specifications & Purity	≥70%
Biochemical and Physiological Mechanisms	Biological stain and redox indicator. Inhibits tau filament formation (IC50= 1.9μM). Also inhibits soluble guanylyl cyclase.
Shipped In	Normal

Associated Targets

DLD Tbio Dihydrolipoyl dehydrogenase, mitochondrial 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLB Tchem DNA polymerase beta 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DLX6 Tbio Homeobox protein DLX-6 0 Activities

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MSTN Tclin Growth/differentiation factor 8 0 Activities

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GMNN Tbio Geminin 0 Activities

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PTH1R Tclin Parathyroid hormone/parathyroid hormone-related peptide receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RAD52 Tchem DNA repair protein RAD52 homolog 1 Activities

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POLH Tchem DNA polymerase eta 0 Activities

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PTPN1 Tchem Tyrosine-protein phosphatase non-receptor type 1 0 Activities

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FTL Tbio Ferritin light chain 0 Activities

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FGB Tbio Fibrinogen beta chain 0 Activities

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KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

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FEN1 Tchem Flap endonuclease 1 0 Activities

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TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic 0 Activities

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SMN1 Tchem Survival motor neuron protein 0 Activities

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SNCA Tchem Alpha-synuclein 0 Activities

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SMAD3 Tchem Mothers against decapentaplegic homolog 3 0 Activities

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TSHR Tclin Thyrotropin receptor 0 Activities

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PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 0 Activities

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POLI Tchem DNA polymerase iota 0 Activities

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RECQL Tbio ATP-dependent DNA helicase Q1 0 Activities

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PKM Tchem Pyruvate kinase PKM 0 Activities

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LHCGR Tclin Lutropin-choriogonadotropic hormone receptor 0 Activities

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MBNL1 Tbio Muscleblind-like protein 1 0 Activities

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CASP6 Tchem Caspase-6 0 Activities

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BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

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ALB Tchem Serum albumin 0 Activities

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MAOA Tclin Amine oxidase [flavin-containing] A 1 Activities

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APP Tclin Amyloid-beta A4 protein 1 Activities

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THRB Tclin Thyroid hormone receptor beta 0 Activities

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MAPT Tclin Microtubule-associated protein tau 2 Activities

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ATM Tchem Serine-protein kinase ATM 0 Activities

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APAF1 Tchem Apoptotic protease-activating factor 1 0 Activities

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GSR Tclin Glutathione reductase, mitochondrial 0 Activities

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IMPA1 Tclin Inositol monophosphatase 1 0 Activities

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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 0 Activities

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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

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NPSR1 Tchem Neuropeptide S receptor 0 Activities

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KDM4A Tchem Lysine-specific demethylase 4A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

Discover Target: MAPK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488180005
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488180005
IUPAC Name	[7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride
INCHI	InChI=1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1
InChi Key	CXKWCBBOMKCUKX-UHFFFAOYSA-M
Canonical SMILES	CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]
Isomeric SMILES	CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]
RTECS	SO5600000
PubChem CID	6099
Molecular Weight	319.85
Beilstein	27395
Reaxy-Rn	3599847

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

20 results found

Lot Number	Certificate Type	Date	Item
K2224732	Certificate of Analysis	Sep 06, 2024	M134389
K2224731	Certificate of Analysis	Sep 06, 2024	M134389
K2224728	Certificate of Analysis	Sep 06, 2024	M134389
K2224724	Certificate of Analysis	Sep 06, 2024	M134389
K2224727	Certificate of Analysis	Sep 06, 2024	M134389
H2219258	Certificate of Analysis	Jun 18, 2024	M134389
H2219259	Certificate of Analysis	Jun 18, 2024	M134389
H2219308	Certificate of Analysis	Jun 18, 2024	M134389
H2219297	Certificate of Analysis	Jun 11, 2024	M134389
G2113202	Certificate of Analysis	Apr 18, 2023	M134389
G2113205	Certificate of Analysis	Apr 18, 2023	M134389
G2113206	Certificate of Analysis	Apr 18, 2023	M134389
B2104143	Certificate of Analysis	Dec 13, 2022	M134389
B2104141	Certificate of Analysis	Dec 13, 2022	M134389
K2224725	Certificate of Analysis	Oct 27, 2022	M134389
K2224729	Certificate of Analysis	Oct 27, 2022	M134389
G2409014	Certificate of Analysis	Oct 27, 2022	M134389
K2316321	Certificate of Analysis	Oct 27, 2022	M134389
L2325027	Certificate of Analysis	Oct 27, 2022	M134389
H2219298	Certificate of Analysis	Jul 01, 2022	M134389

Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 3.2, Max Conc. mM: 10; Solvent:DMSO, Max Conc. mg/mL: 3.2, Max Conc. mM: 10
Flash Point(°C)	14°C
Melt Point(°C)	190°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed H318:Causes serious eye damage
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help.
RTECS	SO5600000
Reaxy-Rn	3599847

Alternative Products

References

1. Chuanjie Liu. (2022) Facile Access to Gleditsia microphylla Galactomannan Hydrogel with Rapid Self-Repair Capacity and Multicyclic Water-Retaining Performance of Sandy Soil. Polymers, 5430 (14): (1-14). [PMID:]

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Methylene blue - ≥70.0%, high purity , CAS No.61-73-4