Metiamide - ≥98%, high purity , CAS No.34839-70-8, Antagonist of H 2 receptor

Item Number
M125130
Grouped product items
SKUSizeAvailabilityPrice Qty
M125130-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$84.90
M125130-5mg
5mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
M125130-10mg
10mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
M125130-25mg
25mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$589.90
M125130-50mg
50mg
Available within 8-12 weeks(?)
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$799.90
M125130-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,129.90

Basic Description

SynonymsSK&F 92058 | 1-Methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)thiourea
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological Mechanisms

Description: IC50 Value: 0.92uM(Ki with glycolaldehyde as the varied substrate for E3) Metiamide is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide. It was an intermediate compound in the development of

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of H 2 receptor
Product Description

Metiamide (SK&F 92058) is a histamine H2-receptor antagonist.

Associated Targets(Human)

HRH2 Tclin Histamine H2 receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 1-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]thiourea
INCHI InChI=1S/C9H16N4S2/c1-7-8(13-6-12-7)5-15-4-3-11-9(14)10-2/h6H,3-5H2,1-2H3,(H,12,13)(H2,10,11,14)
InChi Key FPBPLBWLMYGIQR-UHFFFAOYSA-N
Canonical SMILES CC1=C(N=CN1)CSCCNC(=S)NC
Isomeric SMILES CC1=C(N=CN1)CSCCNC(=S)NC
PubChem CID 1548992
Molecular Weight 244.38

Certificates

Certificate of Analysis(COA)

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9 results found

Lot NumberCertificate TypeDateItem
F2426103Certificate of AnalysisMar 08, 2024 M125130
F2426133Certificate of AnalysisMar 08, 2024 M125130
F2426134Certificate of AnalysisMar 08, 2024 M125130
F2426416Certificate of AnalysisMar 08, 2024 M125130
F2426417Certificate of AnalysisMar 08, 2024 M125130
F2426418Certificate of AnalysisMar 08, 2024 M125130
F2426419Certificate of AnalysisMar 08, 2024 M125130
F2426431Certificate of AnalysisMar 08, 2024 M125130
F2426432Certificate of AnalysisMar 08, 2024 M125130

Chemical and Physical Properties

Solubility(25℃): Water 28.7 mg/mL

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