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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M125130-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $84.90 | |
M125130-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 | |
M125130-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $349.90 | |
M125130-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $589.90 | |
M125130-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $799.90 | |
M125130-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,129.90 |
Synonyms | SK&F 92058 | 1-Methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)thiourea |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Description: IC50 Value: 0.92uM(Ki with glycolaldehyde as the varied substrate for E3) Metiamide is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide. It was an intermediate compound in the development of |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of H 2 receptor |
Product Description | Metiamide (SK&F 92058) is a histamine H2-receptor antagonist. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]thiourea |
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INCHI | InChI=1S/C9H16N4S2/c1-7-8(13-6-12-7)5-15-4-3-11-9(14)10-2/h6H,3-5H2,1-2H3,(H,12,13)(H2,10,11,14) |
InChi Key | FPBPLBWLMYGIQR-UHFFFAOYSA-N |
Canonical SMILES | CC1=C(N=CN1)CSCCNC(=S)NC |
Isomeric SMILES | CC1=C(N=CN1)CSCCNC(=S)NC |
PubChem CID | 1548992 |
Molecular Weight | 244.38 |
PubChem CID | 1548992 |
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CAS Registry No. | 34839-70-8 |
ChEMBL Ligand | CHEMBL275446 |
DrugBank Ligand | DB08805 |
BindingDB Ligand | 81468 |
Wikipedia | Metiamide |
GPCRdb Ligand | metiamide |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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F2426103 | Certificate of Analysis | Mar 08, 2024 | M125130 |
F2426133 | Certificate of Analysis | Mar 08, 2024 | M125130 |
F2426134 | Certificate of Analysis | Mar 08, 2024 | M125130 |
F2426416 | Certificate of Analysis | Mar 08, 2024 | M125130 |
F2426417 | Certificate of Analysis | Mar 08, 2024 | M125130 |
F2426418 | Certificate of Analysis | Mar 08, 2024 | M125130 |
F2426419 | Certificate of Analysis | Mar 08, 2024 | M125130 |
F2426431 | Certificate of Analysis | Mar 08, 2024 | M125130 |
F2426432 | Certificate of Analysis | Mar 08, 2024 | M125130 |
Solubility | (25℃): Water 28.7 mg/mL |
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