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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M647943-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $110.90 | |
M647943-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $180.90 | |
M647943-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $360.90 | |
M647943-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $580.90 | |
M647943-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $920.90 |
Specifications & Purity | ≥99% |
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Biochemical and Physiological Mechanisms | MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy In Vitro MF-094 has <30% inhibitory activity for a panel of 22 USPs assays at 10 uM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 120 nM (USP30) |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-[(2S)-1-[[5-(tert-butylsulfamoyl)naphthalen-1-yl]amino]-1-oxo-3-phenylpropan-2-yl]cyclohexanecarboxamide |
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INCHI | InChI=1S/C30H37N3O4S/c1-30(2,3)33-38(36,37)27-19-11-16-23-24(27)17-10-18-25(23)31-29(35)26(20-21-12-6-4-7-13-21)32-28(34)22-14-8-5-9-15-22/h4,6-7,10-13,16-19,22,26,33H,5,8-9,14-15,20H2,1-3H3,(H,31,35)(H,32,34)/t26-/m0/s1 |
InChi Key | DQXORJHBZHLLTE-SANMLTNESA-N |
Canonical SMILES | CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)C(CC3=CC=CC=C3)NC(=O)C4CCCCC4 |
Isomeric SMILES | CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)C4CCCCC4 |
PubChem CID | 138319686 |
MeSH Entry Terms | MF-094;N-((2S)-1-((5-(tert-butylsulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide |
Molecular Weight | 535.70 |
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Solubility | DMSO : 125 mg/mL (233.34 mM; Need ultrasonic) |
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