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MF-094 - 99%, high purity , CAS No.2241025-68-1

  • ≥99%
Item Number
M647943
Grouped product items
SKUSizeAvailabilityPrice Qty
M647943-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$110.90
M647943-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$180.90
M647943-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$360.90
M647943-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$580.90
M647943-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$920.90
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View related series
Cell Cycle/DNA Damage Deubiquitinase

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsMF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy

In Vitro

MF-094 has <30% inhibitory activity for a panel of 22 USPs assays at 10 uM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 120 nM (USP30)

Associated Targets(Human)

USP30 Tchem Ubiquitin carboxyl-terminal hydrolase 30 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
USP5 Tchem Ubiquitin carboxyl-terminal hydrolase 5 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP2 Tbio Ubiquitin carboxyl-terminal hydrolase 2 (8818 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP14 Tchem Ubiquitin carboxyl-terminal hydrolase 14 (35 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP7 Tchem Ubiquitin carboxyl-terminal hydrolase 7 (837 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP21 Tbio Ubiquitin carboxyl-terminal hydrolase 21 (108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP28 Tchem Ubiquitin carboxyl-terminal hydrolase 28 (268 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP8 Tchem Ubiquitin carboxyl-terminal hydrolase 8 (245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP9X Tbio Probable ubiquitin carboxyl-terminal hydrolase FAF-X (500 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP4 Tchem Ubiquitin carboxyl-terminal hydrolase 4 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP20 Tbio Ubiquitin carboxyl-terminal hydrolase 20 (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP25 Tchem Ubiquitin carboxyl-terminal hydrolase 25 (268 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP19 Tbio Ubiquitin carboxyl-terminal hydrolase 19 (667 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP30 Tchem Ubiquitin carboxyl-terminal hydrolase 30 (944 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP15 Tbio Ubiquitin carboxyl-terminal hydrolase 15 (7 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP27X Tbio Ubiquitin carboxyl-terminal hydrolase 27 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP6 Tbio Ubiquitin carboxyl-terminal hydrolase 6 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP11 Tbio Ubiquitin carboxyl-terminal hydrolase 11 (16 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP45 Tbio Ubiquitin carboxyl-terminal hydrolase 45 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYLD Tbio Ubiquitin carboxyl-terminal hydrolase CYLD (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP36 Tbio Ubiquitin carboxyl-terminal hydrolase 36 (9 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP35 Tbio Ubiquitin carboxyl-terminal hydrolase 35 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP16 Tbio Ubiquitin carboxyl-terminal hydrolase 16 (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name N-[(2S)-1-[[5-(tert-butylsulfamoyl)naphthalen-1-yl]amino]-1-oxo-3-phenylpropan-2-yl]cyclohexanecarboxamide
INCHI InChI=1S/C30H37N3O4S/c1-30(2,3)33-38(36,37)27-19-11-16-23-24(27)17-10-18-25(23)31-29(35)26(20-21-12-6-4-7-13-21)32-28(34)22-14-8-5-9-15-22/h4,6-7,10-13,16-19,22,26,33H,5,8-9,14-15,20H2,1-3H3,(H,31,35)(H,32,34)/t26-/m0/s1
InChi Key DQXORJHBZHLLTE-SANMLTNESA-N
Canonical SMILES CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)C(CC3=CC=CC=C3)NC(=O)C4CCCCC4
Isomeric SMILES CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)C4CCCCC4
PubChem CID 138319686
MeSH Entry Terms MF-094;N-((2S)-1-((5-(tert-butylsulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide
Molecular Weight 535.70

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 125 mg/mL (233.34 mM; Need ultrasonic)

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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