Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M275983-10mg | 10mg | In stock | $149.90 | |
M275983-25mg | 25mg | In stock | $335.90 | |
M275983-50mg | 50mg | In stock | $618.90 | |
M275983-100mg | 100mg | In stock | $1,113.90 |
Selective α7 nACh receptor antagonist
Synonyms | N,N,N-triethyl-2-[4-[(1E)-2-phenylethenyl]phenoxy]-ethanaminium, monoiodide | NSC706725 | UNII-19B3530KQ6 | SCHEMBL27296 | HMS2231N08 | HY-107672 | DTXCID0025781 | Stilonio ioduro | SR-01000597761-1 | STILONIUM IODIDE [INN] | Tox21_500765 | (+-)-BN-1270 | |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Selective α7 nACh receptor antagonist (K i values are 0.1 and 84 μM for preventing α-Bungarotoxin binding to α7 and α4β2 subtypes respectively). Decreases Egr-1 levels. Shows antiangiogenic effects. |
Storage Temp | Store at -20°C,Argon charged,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | triethyl-[2-[4-[(E)-2-phenylethenyl]phenoxy]ethyl]azanium;iodide |
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INCHI | InChI=1S/C22H30NO.HI/c1-4-23(5-2,6-3)18-19-24-22-16-14-21(15-17-22)13-12-20-10-8-7-9-11-20;/h7-17H,4-6,18-19H2,1-3H3;1H/q+1;/p-1/b13-12+; |
InChi Key | RDTKUZXIHMTSJO-UEIGIMKUSA-M |
Canonical SMILES | CC[N+](CC)(CC)CCOC1=CC=C(C=C1)C=CC2=CC=CC=C2.[I-] |
Isomeric SMILES | CC[N+](CC)(CC)CCOC1=CC=C(C=C1)/C=C/C2=CC=CC=C2.[I-] |
PubChem CID | 6433339 |
Molecular Weight | 451.38 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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A2312095 | Certificate of Analysis | Oct 18, 2023 | M275983 |
A2312123 | Certificate of Analysis | Oct 18, 2023 | M275983 |
A2312317 | Certificate of Analysis | Oct 18, 2023 | M275983 |
A2312343 | Certificate of Analysis | Oct 18, 2023 | M275983 |
Solubility | Soluble in ethanol to 10 mM and in DMSO to 10 mM |
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Sensitivity | Air sensitive |