Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M129226-50mg | 50mg | In stock | $48.90 | |
M129226-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $181.90 | |
M129226-1g | 1g | In stock | $539.90 | |
M129226-5g | 5g | In stock | $1,853.90 |
Multiple receptor antagonist. Activity at 5-HT 2 , H 1 and α 2 receptors.
Synonyms | Mianserin hydrochloride | 21535-47-7 | Mianserin HCl | Mianserine hydrochloride | Athymil | Bolvidon | Tolvon | ORG GB 94 | Mianserin (hydrochloride) | Lerivon | Tetramide | mianserine HCl | 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride | MLS000 |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Mianserin hydrochloride is a 5-HT2/5-HT1 antagonist. It has moderate affinity for 5-ht6 and is non-selective 5-HT2 receptor antagonist. Has moderate affinity for 5-HT6.Multiple receptor antagonist. Shows activity at 5-HT 2 , H 1 and α 2 receptors. Display |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | A non-selective 5-HT2 receptor antagonist with moderate affinity for 5-HT6. |
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IUPAC Name | 5-methyl-2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaene;hydrochloride |
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INCHI | InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H |
InChi Key | YNPFMWCWRVTGKJ-UHFFFAOYSA-N |
Canonical SMILES | CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42.Cl |
Isomeric SMILES | CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42.Cl |
WGK Germany | 3 |
RTECS | HP8780000 |
PubChem CID | 68551 |
Molecular Weight | 300.83 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2221099 | Certificate of Analysis | May 21, 2024 | M129226 |
G2221102 | Certificate of Analysis | May 21, 2024 | M129226 |
G2221106 | Certificate of Analysis | May 21, 2024 | M129226 |
G1918208 | Certificate of Analysis | Feb 09, 2023 | M129226 |
F1525053 | Certificate of Analysis | Jan 18, 2023 | M129226 |
Solubility | Soluble in water (3.4 mg/ml), ethanol (5.6 mg/ml), methanol, and DMSO (60 mg/ml) at 25 °C. |
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Sensitivity | Moisture & Heat sensitive |
Melt Point(°C) | 284°C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H302:Harmful if swallowed H370:Causes damage to organs H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P308+P316:IF exposed or concerned: Get emergency medical help immediately. |
WGK Germany | 3 |
RTECS | HP8780000 |
Merck Index | 6172 |