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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M649177-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $39.90 | |
M649177-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $64.90 | |
M649177-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $129.90 | |
M649177-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $209.90 |
Synonyms | (R)-N-(2-(4'-(2-(Methylsulfonamido)ethyl)-[1,1'-biphenyl]-4-yl)propyl)propane-2-sulfonamide | LY451395 | 2-Propanesulfonamide, N-[(2R)-2-[4'-[2-[(methylsulfonyl)amino]ethyl][1,1'-biphenyl]-4-yl]propyl]- |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Action Type | POSITIVE ALLOSTERIC MODULATOR |
Mechanism of action | Glutamate receptor ionotropic AMPA positive allosteric modulator |
ALogP | 3.4 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-[(2R)-2-[4-[4-[2-(methanesulfonamido)ethyl]phenyl]phenyl]propyl]propane-2-sulfonamide |
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INCHI | InChI=1S/C21H30N2O4S2/c1-16(2)29(26,27)23-15-17(3)19-9-11-21(12-10-19)20-7-5-18(6-8-20)13-14-22-28(4,24)25/h5-12,16-17,22-23H,13-15H2,1-4H3/t17-/m0/s1 |
InChi Key | ULRDYYKSPCRXAJ-KRWDZBQOSA-N |
Canonical SMILES | CC(C)S(=O)(=O)NCC(C)C1=CC=C(C=C1)C2=CC=C(C=C2)CCNS(=O)(=O)C |
Isomeric SMILES | C[C@@H](CNS(=O)(=O)C(C)C)C1=CC=C(C=C1)C2=CC=C(C=C2)CCNS(=O)(=O)C |
Alternate CAS | 375345-95-2 |
PubChem CID | 9889366 |
MeSH Entry Terms | LY 451395;LY-451395;LY451395;N-((2-(4'-(2-(methylsulfonyl)amino)ethyl)(1,1'-biphenyl)-4-yl)propyl)-2-propanesulfonamide |
Molecular Weight | 438.60 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H2416587 | Certificate of Analysis | May 06, 2024 | M649177 |
H2416588 | Certificate of Analysis | May 06, 2024 | M649177 |
H2416589 | Certificate of Analysis | May 06, 2024 | M649177 |
H2416590 | Certificate of Analysis | May 06, 2024 | M649177 |
Solubility | DMSO : ≥ 25 mg/mL (57.00 mM) |
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