Mibefradil dihydrochloride - ≥98%, high purity , Voltage-gated T-type calcium channel blocker, CAS No.116666-63-8, Voltage-gated T-type calcium channel blocker

Item Number

M275143

• Synonyms: HY-15553A | Mibefradil hydrochloride | FD5011 | RO 40-5967/001 | MIBEFRADIL DIHYDROCHLORIDE [MI] | MIBEFRADIL HYDROCHLORIDE [WHO-DD] | UNII-842TUP3PQ8 | [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methyl-amino]ethyl]-6-fluoro-1-isopropyl-tetralin-2-yl]
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Ca 2+ channel blocker. Shows moderate selectivity for T-type channels (IC 50 values are 2.7 and 18.6 μM for T-type and L-type respectively). Shows antihypertensive effects in vivo. Orally active.
• Storage Temp: Store at -20°C,Argon charged,Desiccated
• Shipped In: Ice chest + Ice pads
• Action Type: BLOCKER
• Mechanism of action: Voltage-gated T-type calcium channel blocker
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively)