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Minodronic acid - 99%, high purity , Farnesyl diphosphate synthase inhibitor, CAS No.180064-38-4, Farnesyl diphosphate synthase inhibitor
Basic Description Synonyms (1-hydroxy-2-imidazo[1,2-a]pyridin-3-yl-1-phosphonoethyl)phosphonic acid | (1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl)diphosphonicacid | AM84629 | Onobis | (1-Hydroxy-2-imidazo[1,1-bisphos phonate | CS-0006290 | Recalbon | s5057 | Phosphonic Specifications & Purity Moligand™, ≥99% Biochemical and Physiological Mechanisms Minodronic acid (YM529, ONO-5920) is a third-generation nitrogen-cotaining bisphosphonate that is used for the treatment of osteoporosis. Minodronic acid is an aminobisphosphonate that is a selective antagonist of purinergic P2X2/3 receptors involved in p Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type INHIBITOR Mechanism of action Farnesyl diphosphate synthase inhibitor Product Description Information
Minodronic acid Minodronic acid (YM529, ONO-5920) is a third-generation nitrogen-cotaining bisphosphonate that is used for the treatment of osteoporosis. Minodronic acid is an aminobisphosphonate that is a selective antagonist of purinergic P2X2/3 receptors involved in pain.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (1-hydroxy-2-imidazo[1,2-a]pyridin-3-yl-1-phosphonoethyl)phosphonic acid INCHI InChI=1S/C9H12N2O7P2/c12-9(19(13,14)15,20(16,17)18)5-7-6-10-8-3-1-2-4-11(7)8/h1-4,6,12H,5H2,(H2,13,14,15)(H2,16,17,18) InChi Key VMMKGHQPQIEGSQ-UHFFFAOYSA-N Canonical SMILES C1=CC2=NC=C(N2C=C1)CC(O)(P(=O)(O)O)P(=O)(O)O Isomeric SMILES C1=CC2=NC=C(N2C=C1)CC(O)(P(=O)(O)O)P(=O)(O)O PubChem CID 130956 Molecular Weight 322.15
Chemical and Physical Properties Solubility Solubility (25°C) In vitro 0.5MNAOH 3.06 mg/mL (9.49 mM); DMSO: 0.001 mg/mL (0.0 mM); Water: Insoluble;
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS08 Signal Danger Hazard Statements H301: Toxic if swallowed
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P318: if exposed or concerned, get medical advice.
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