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Mirin - ≥99%(HPLC), high purity , CAS No.1198097-97-0
MRN-ATM pathway inhibitor
Basic Description Synonyms AC-32950 | AS-55824 | CCG-208657 | SCHEMBL21296287 | (5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone | ZLA95300 | M3303 | (Z)-2-amino-5-(4-hydroxybenzylidene)thiazol-4(5H)-one | 1198097-97-0 | A910477 | Mrn-atm pathway inhibitor,mirin | YXB09 Specifications & Purity ≥99%(HPLC) Biochemical and Physiological Mechanisms Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor that blocks the 3' and 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC50= 12μM) and induces G2cell cycle arrest. Also blocks homology-directed repa Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (5Z)-5-[(4-hydroxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one INCHI InChI=1S/C10H8N2O2S/c11-10-12-9(14)8(15-10)5-6-1-3-7(13)4-2-6/h1-5,13H,(H2,11,12,14)/b8-5- InChi Key YBHQCJILTOVLHD-YVMONPNESA-N Canonical SMILES C1=CC(=CC=C1C=C2C(=O)NC(=N)S2)O Isomeric SMILES C1=CC(=CC=C1/C=C\2/C(=O)NC(=N)S2)O PubChem CID 137319711 Molecular Weight 220.25
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 22.02, Max Conc. mM: 100 Sensitivity Air Sensitive,Heat Sensitive Melt Point(°C) 298 °C
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I2205076