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MK-2461 - 98%, high purity , Hepatocyte growth factor receptor inhibitor, CAS No.917879-39-1, Hepatocyte growth factor receptor inhibitor

Moligand™
≥98%

CAS#: 917879-39-1
Formula: C₂₄H₂₅N₅O₅S
Molecular Weight: 495.55
PubChem CID: 44137946

Item Number

M129777

Grouped product items
SKU	Size	Availability	Price
M129777-1mg	1mg	In stock	$47.90
M129777-5mg	5mg	In stock	$195.90
M129777-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$347.90

View related series

fibroblast growth factor receptor 1 Inhibitor fibroblast growth factor receptor 2 Inhibitor fibroblast growth factor receptor 3 Inhibitor fms related receptor tyrosine kinase 1 Inhibitor fms related receptor tyrosine kinase 3 Inhibitor fms related receptor tyrosine kinase 4 Inhibitor kinase insert domain receptor Inhibitor macrophage stimulating 1 receptor Inhibitor MER proto-oncogene，tyrosine kinase Inhibitor MET proto-oncogene，receptor tyrosine kinase Inhibitor neurotrophic receptor tyrosine kinase 1 Inhibitor neurotrophic receptor tyrosine kinase 2 Inhibitor platelet derived growth factor receptor beta Inhibitor

Basic Description

Synonyms	MK-2461\|917879-39-1\|MK 2461\|MK2461\|n-((2r)-1,4-dioxan-2-ylmethyl)-n-methyl-n'-[3-(1-methyl-1h-pyrazol-4-yl)-5-oxo-5h-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide\|4200RD53XF\|Sulfamide, N-((2R)-1,4-dioxan-2-ylmethyl)-N-methyl-N'-(3-(1-methyl-1H-pyrazol
Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Hepatocyte growth factor receptor inhibitor

Associated Targets

MST1R Tchem Macrophage-stimulating protein receptor 2 Activities

Discover Target: MST1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FLT4 Tclin Vascular endothelial growth factor receptor 3 1 Activities

Discover Target: FLT4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FLT3 Tclin Receptor-type tyrosine-protein kinase FLT3 2 Activities

Discover Target: FLT3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FGFR1 Tclin Fibroblast growth factor receptor 1 1 Activities

Discover Target: FGFR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FGFR2 Tclin Fibroblast growth factor receptor 2 1 Activities

Discover Target: FGFR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FGFR3 Tclin Fibroblast growth factor receptor 3 1 Activities

Discover Target: FGFR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MET Tclin Hepatocyte growth factor receptor 15 Activities

Discover Target: MET

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MERTK Tchem Tyrosine-protein kinase Mer 2 Activities

Discover Target: MERTK

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDGFRB Tclin Platelet-derived growth factor receptor beta 1 Activities

Discover Target: PDGFRB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FLT1 Tclin Vascular endothelial growth factor receptor 1 2 Activities

Discover Target: FLT1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDR Tclin Vascular endothelial growth factor receptor 2 1 Activities

Discover Target: KDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NTRK2 Tclin BDNF/NT-3 growth factors receptor 1 Activities

Discover Target: NTRK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NTRK1 Tclin High affinity nerve growth factor receptor 1 Activities

Discover Target: NTRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	14-[[[(2R)-1,4-dioxan-2-yl]methyl-methylsulfamoyl]amino]-5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
INCHI	InChI=1S/C24H25N5O5S/c1-28-13-18(12-26-28)17-9-22-23(25-11-17)6-4-16-3-5-19(10-21(16)24(22)30)27-35(31,32)29(2)14-20-15-33-7-8-34-20/h3-6,9-13,20,27H,7-8,14-15H2,1-2H3/t20-/m1/s1
InChi Key	JGEBLDKNWBUGRZ-HXUWFJFHSA-N
Canonical SMILES	CN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)NS(=O)(=O)N(C)CC5COCCO5)N=C2
Isomeric SMILES	CN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)NS(=O)(=O)N(C)C[C@@H]5COCCO5)N=C2
PubChem CID	44137946
Molecular Weight	495.55

PubChem CID

44137946

ChEMBL Ligand

CHEMBL1822792

CAS Registry No.

917879-39-1

Certificates

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3 results found

Lot Number	Certificate Type	Date	Item
I2203359	Certificate of Analysis	Jun 18, 2024	M129777
I2203363	Certificate of Analysis	Jun 18, 2024	M129777
I2203357	Certificate of Analysis	Jun 25, 2022	M129777

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