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ML-167 - 10mM in DMSO, high purity , CAS No.1285702-20-6
Potent, highly selective Cdc2-like kinase 4 inhibitor
Basic Description Synonyms ML167 | 1285702-20-6 | (5-(4-(((5-Methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol | ML-167 | CHEMBL1604618 | CID 44968231 | [5-(4-{[(5-METHYLFURAN-2-YL)METHYL]AMINO}QUINAZOLIN-6-YL)FURAN-2-YL]METHANOL | (5-(4-((5-methylfuran-2-yl)methylamino)quinazoli Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Potent, highly selective Cdc2-like kinase 4 inhibitor (IC 50 = 136 nM). Cell-permeable. Putatively ATP-competitive Clk4 inhibitor.ML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4, >10-fold selec Storage Temp Store at -80°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name [5-[4-[(5-methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol INCHI InChI=1S/C19H17N3O3/c1-12-2-4-14(24-12)9-20-19-16-8-13(3-6-17(16)21-11-22-19)18-7-5-15(10-23)25-18/h2-8,11,23H,9-10H2,1H3,(H,20,21,22) InChi Key ROCFOIBAEVAOLQ-UHFFFAOYSA-N Canonical SMILES CC1=CC=C(O1)CNC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CO Isomeric SMILES CC1=CC=C(O1)CNC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CO PubChem CID 44968231 Molecular Weight 335.36
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H302: Harmful if swallowed
Precautionary Statements P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P301+P317: IF SWALLOWED: Get medical help.
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