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ML 228 - ≥98%(HPLC), high purity , CAS No.1357171-62-0
Basic Description Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms HIF pathway activator (EC50values are 1.23 and 1.4μM for HRE gene reporter assay and HIF-1αnuclear translocation assay respectively); acts via chelation of iron, independently of PHD. Also exhibits > 80% inhibition of the human A3receptor, dopamine transp Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers Pubchem Sid 488201356 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488201356 IUPAC Name 6-phenyl-N-[(4-phenylphenyl)methyl]-3-pyridin-2-yl-1,2,4-triazin-5-amine INCHI InChI=1S/C27H21N5/c1-3-9-21(10-4-1)22-16-14-20(15-17-22)19-29-27-25(23-11-5-2-6-12-23)31-32-26(30-27)24-13-7-8-18-28-24/h1-18H,19H2,(H,29,30,32) InChi Key QNRODODTMXCRKU-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C=C1)C2=CC=C(C=C2)CNC3=C(N=NC(=N3)C4=CC=CC=N4)C5=CC=CC=C5 Isomeric SMILES C1=CC=C(C=C1)C2=CC=C(C=C2)CNC3=C(N=NC(=N3)C4=CC=CC=N4)C5=CC=CC=C5 PubChem CID 46742353 Molecular Weight 415.49
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 41.55, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 8.31, Max Conc. mM: 20
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C23181153