ML008 - 98%, high purity , CAS No.442898-34-2

  • ≥98%
Item Number
M412844
Grouped product items
SKUSizeAvailabilityPrice Qty
M412844-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
M412844-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$93.90
M412844-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$159.90
M412844-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
M412844-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$469.90

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsML008 (NCGC00092410) is a potent and selective glucocerebrosidase inhibitor with IC50 of 31 nM.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

ML008 (NCGC00092410) is a potent and selective glucocerebrosidase inhibitor with IC50 of 31 nM.

Associated Targets(Human)

GBA Tclin Glucosylceramidase (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GLA Tclin Alpha-galactosidase A (5444 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

melA Alpha-galactosidase (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name N-(4-methyl-2-morpholin-4-ylquinolin-6-yl)cyclohexanecarboxamide
INCHI InChI=1S/C21H27N3O2/c1-15-13-20(24-9-11-26-12-10-24)23-19-8-7-17(14-18(15)19)22-21(25)16-5-3-2-4-6-16/h7-8,13-14,16H,2-6,9-12H2,1H3,(H,22,25)
InChi Key BXVNPOBNVRBOOV-UHFFFAOYSA-N
Canonical SMILES CC1=CC(=NC2=C1C=C(C=C2)NC(=O)C3CCCCC3)N4CCOCC4
Isomeric SMILES CC1=CC(=NC2=C1C=C(C=C2)NC(=O)C3CCCCC3)N4CCOCC4
PubChem CID 5067281
Molecular Weight 353.46

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
L2321226Certificate of AnalysisDec 04, 2023 M412844
L2321227Certificate of AnalysisDec 04, 2023 M412844
L2321235Certificate of AnalysisDec 04, 2023 M412844
L2321236Certificate of AnalysisDec 04, 2023 M412844
L2321237Certificate of AnalysisDec 04, 2023 M412844

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