ML130 (Nodinitib-1) - ≥99%, high purity , CAS No.799264-47-4, Inhibitor of nucleotide binding oligomerization domain containing 1;Inhibitor of nucleotide binding oligomerization domain containing 2

Item Number

M129713

• Synonyms: Nodinitib-1 | 799264-47-4 | ML130 | 1-Tosyl-1H-benzo[d]imidazol-2-amine | 1-(4-methylphenyl)sulfonylbenzimidazol-2-amine | Noditinib-1 | ML130 (Nodinitib-1) | ML130;CID-1088438 | MLS001201458 | 1-(Toluene-4-sulfonyl)-1H-benzoimidazol-2-ylamine | ML 130 | ML-130 | SMR000523991 | No
• Specifications & Purity: Moligand™, ≥99%
• Biochemical and Physiological Mechanisms: Potent, selective NOD1 inhibitor (IC 50 = 560 nM). Inhibits NOD1-induced NF-κB activation in vitro . Cell-permeable.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of nucleotide binding oligomerization domain containing 1;Inhibitor of nucleotide binding oligomerization domain containing 2
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

ML130 (Nodinitib-1) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2