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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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M647561-2mg | 2mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $62.90 | |
M647561-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $144.90 | |
M647561-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $228.90 | |
M647561-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $492.90 | |
M647561-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $840.90 |
Specifications & Purity | ≥99% |
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Biochemical and Physiological Mechanisms | ML314 is a potent molecule agonist of NTR1 (EC 50 = 1.9 μM); showed good selectivity against NTR2 and GPR35 , but does not stimulate Ca 2+ mobilization. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | ML314 is a potent molecule agonist of NTR1 (EC 50 = 1.9 μM); showed good selectivity against NTR2 and GPR35 , but does not stimulate Ca 2+ mobilization. Form:Solid IC50& Target:NTR1 |
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IUPAC Name | 2-cyclopropyl-6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline |
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INCHI | InChI=1S/C24H28N4O3/c1-29-20-7-5-4-6-19(20)27-10-12-28(13-11-27)24-17-14-21(30-2)22(31-3)15-18(17)25-23(26-24)16-8-9-16/h4-7,14-16H,8-13H2,1-3H3 |
InChi Key | SWEOAXMICIJCQC-UHFFFAOYSA-N |
Canonical SMILES | COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5 |
Isomeric SMILES | COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5 |
PubChem CID | 53245590 |
MeSH Entry Terms | 2-cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline;ML314 compound |
Molecular Weight | 420.50 |
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Solubility | DMSO : 50 mg/mL (118.91 mM; Need ultrasonic) |
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