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MMP-2 Inhibitor II - ≥98%, high purity , CAS No.869577-51-5

  • ≥98%
Item Number
M338117
Grouped product items
SKUSizeAvailabilityPrice Qty
M338117-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$218.90
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an irreversible inhibitor of MMP-2 through active-site binding

Basic Description

Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

MMP-2 Inhibitor II is an oxirane analog of SB-3CT, pMS that is reported to be an irreversible inhibitor of MMP-2 through active-site binding. Although reported to be less potent, it has also been shown enhanced selectivity towards MMP-2 than SB-3CT, pMS. MMP-2 Inhibitor II is an inhibitor of MMP-1.

Product Properties

Ki DataMMP-2: Ki= 2.4 μM; MMP-7: Ki= 379 μM; MMP-1: Ki= 45 μM

Associated Targets(Human)

MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP14 Tchem Matrix metalloproteinase 14 (1592 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP7 Tchem Matrix metalloproteinase 7 (1073 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mmp2 Matrix metalloproteinase-2 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name N-[4-[4-(oxiran-2-ylmethylsulfonyl)phenoxy]phenyl]methanesulfonamide
INCHI InChI=1S/C16H17NO6S2/c1-24(18,19)17-12-2-4-13(5-3-12)23-14-6-8-16(9-7-14)25(20,21)11-15-10-22-15/h2-9,15,17H,10-11H2,1H3
InChi Key ADEXXMLIERNFQB-UHFFFAOYSA-N
Canonical SMILES CS(=O)(=O)NC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)CC3CO3
Isomeric SMILES CS(=O)(=O)NC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)CC3CO3
PubChem CID 15940371
Molecular Weight 383.4

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO (200 mg/ml).
Refractive Indexn20D1.62 (Predicted)
Boil Point(°C)~591.7° C at 760 mmHg (Predicted)
Melt Point(°C)227.51° C (Predicted)

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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