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MN 64 - 10mM in DMSO, high purity , CAS No.92831-11-3
Basic Description
| Synonyms | mn-64 | 92831-11-3 | MN 64 | 4'-Isopropylflavone | 2-(4-Isopropylpheny)-4H-chroMen-4-one | 2-(4-propan-2-ylphenyl)chromen-4-one | 2-(4-isopropylphenyl)-4H-chromen-4-one | 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one | CHEMBL2431867 | 2-[4-(propan-2-yl)phenyl]-4H-chrom |
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| Specifications & Purity | 10mM in DMSO |
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| Biochemical and Physiological Mechanisms | MN-64 is a potent inhibitor of TNKS1 and TNKS2 with IC50 value of 6 and 72 nM, respectively. |
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| Storage Temp | Store at -80°C |
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| Shipped In | Ice chest + Ice pads |
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| Product Description | Information MN 64 MN-64 is a potent inhibitor of TNKS1 and TNKS2 with IC50 value of 6 and 72 nM, respectively. Targets TNKS1 ; TNKS2 6 nM; 72 nM In vitro MN-64 inhibits WNT/β-catenin signaling-dependent Super-TopFlash (STF) luciferase activity. |
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Product Properties
| ALogP | 4.33 |
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| Rotatable Bond | 2 |
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Associated Targets(Human)
Associated Targets(non-human)
Names and Identifiers
| IUPAC Name | 2-(4-propan-2-ylphenyl)chromen-4-one |
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| INCHI | InChI=1S/C18H16O2/c1-12(2)13-7-9-14(10-8-13)18-11-16(19)15-5-3-4-6-17(15)20-18/h3-12H,1-2H3 |
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| InChi Key | PYTOHIUBXSJKQH-UHFFFAOYSA-N |
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| Canonical SMILES | CC(C)C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2 |
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| Isomeric SMILES | CC(C)C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2 |
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| PubChem CID | 2802462 |
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| Molecular Weight | 264.32 |
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Chemical and Physical Properties
| DMSO(mg / mL) Max Solubility | 53 |
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| DMSO(mM) Max Solubility | 200.514527845036 |
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| Water(mg / mL) Max Solubility | ＜1 |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS06 |
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| Signal | Danger |
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| Hazard Statements | H301:Toxic if swallowed |
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| Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
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