MNI-136 , CAS No.946619-20-1, Allosteric modulator of mGlu 2 receptor;Allosteric modulator of mGlu 3 receptor

Item Number
M611977
Grouped product items
SKUSizeAvailabilityPrice Qty
M611977-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,300.90
M611977-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90

Basic Description

SynonymsMNI 136
Specifications & PurityMoligand™
GradeMoligand™
Action TypeALLOSTERIC MODULATOR
Mechanism of actionAllosteric modulator of mGlu 2 receptor;Allosteric modulator of mGlu 3 receptor

Associated Targets(Human)

GRM2 Tchem Metabotropic glutamate receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM3 Tchem Metabotropic glutamate receptor 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 8-bromo-5-[3-(pyridin-4-yl)phenyl]-1,2,3,4-tetrahydro-1,6-benzodiazocin-2-one
INCHI InChI=1S/C21H16BrN3O/c22-17-4-5-19-20(13-17)24-18(6-7-21(26)25-19)16-3-1-2-15(12-16)14-8-10-23-11-9-14/h1-5,8-13H,6-7H2,(H,25,26)/b24-18+
InChi Key BLAQAVITPVXJJS-HKOYGPOVSA-N
Canonical SMILES O=C1CCC(=Nc2c(N1)ccc(c2)Br)c1cccc(c1)c1ccncc1
Isomeric SMILES C1CC(=O)NC2=C(C=C(C=C2)Br)N=C1C3=CC=CC(=C3)C4=CC=NC=C4
PubChem CID 73755192

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