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Monomethyl Fumarate - 10mM in DMSO, high purity , CAS No.2756-87-8

  • Moligand™
  • 10mM in DMSO
Item Number
M422970
Grouped product items
SKUSizeAvailabilityPrice Qty
M422970-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$69.90
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Activator of Nrf2 pathway; primary metabolite ofDMF(Cat. No. 4512)

Basic Description

SynonymsMonomethyl fumarate|2756-87-8|4-methoxy-4-oxobut-2-enoic acid|mono-Methyl fumarate|Methyl hydrogen fumarate|Fumaric acid monomethyl ester|(E)-4-methoxy-4-oxobut-2-enoic acid|Bafiertam|(2E)-4-Methoxy-4-oxobut-2-enoic acid|UNII-45IUB1PX8R|45IUB1PX8R|monomet
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsNuclear factor (erythroid-derived-2)-like 2 (Nrf2) pathway activator. Also exhibits agonist activity at GPR109A. Primary metabolite ofDMF.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

mono-Methyl fumarate can be used as a reactant to synthesize: · Jumonji C domain-containing histone demethylases (JCHDMs) inhibitor. · (-)-Xylariamide A, a fungal metabolite. · (±)-Methoxyfumimycin ethyl ester, a potential bacterial peptide deformylase inhibitor. It is also a wide spectrum antibacterial agent with a powerful antioxidant activity.

Product Properties

ALogP0.4

Associated Targets

CA5A Tclin Carbonic anhydrase 5A, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HCAR2 Tclin Hydroxycarboxylic acid receptor 2 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA5B Tclin Carbonic anhydrase 5B, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA1 Tclin Carbonic anhydrase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA2 Tclin Carbonic anhydrase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (E)-4-methoxy-4-oxobut-2-enoic acid
INCHI InChI=1S/C5H6O4/c1-9-5(8)3-2-4(6)7/h2-3H,1H3,(H,6,7)/b3-2+
InChi Key NKHAVTQWNUWKEO-NSCUHMNNSA-N
Canonical SMILES COC(=O)C=CC(=O)O
Isomeric SMILES COC(=O)/C=C/C(=O)O
WGK Germany 3
PubChem CID 5369209
Molecular Weight 130.1

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Melt Point(°C)145-149°C

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H318:Causes serious eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

WGK Germany 3

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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