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Monomethyl Fumarate - 10mM in DMSO, high purity , CAS No.2756-87-8
Activator of Nrf2 pathway; primary metabolite ofDMF(Cat. No. 4512)
Basic Description Synonyms Monomethyl fumarate | 2756-87-8 | 4-methoxy-4-oxobut-2-enoic acid | mono-Methyl fumarate | Methyl hydrogen fumarate | Fumaric acid monomethyl ester | (E)-4-methoxy-4-oxobut-2-enoic acid | Bafiertam | (2E)-4-Methoxy-4-oxobut-2-enoic acid | UNII-45IUB1PX8R | 45IUB1PX8R | monomet Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms Nuclear factor (erythroid-derived-2)-like 2 (Nrf2) pathway activator. Also exhibits agonist activity at GPR109A. Primary metabolite ofDMF. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description mono-Methyl fumarate can be used as a reactant to synthesize: · Jumonji C domain-containing histone demethylases (JCHDMs) inhibitor. · (-)-Xylariamide A, a fungal metabolite. · (±)-Methoxyfumimycin ethyl ester, a potential bacterial peptide deformylase inhibitor. It is also a wide spectrum antibacterial agent with a powerful antioxidant activity.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (E)-4-methoxy-4-oxobut-2-enoic acid INCHI InChI=1S/C5H6O4/c1-9-5(8)3-2-4(6)7/h2-3H,1H3,(H,6,7)/b3-2+ InChi Key NKHAVTQWNUWKEO-NSCUHMNNSA-N Canonical SMILES COC(=O)C=CC(=O)O Isomeric SMILES COC(=O)/C=C/C(=O)O WGK Germany 3 PubChem CID 5369209 Molecular Weight 130.1
Chemical and Physical Properties Safety and Hazards(GHS) Pictogram(s) GHS05 Signal Danger Hazard Statements H318: Causes serious eye damage
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P305+P354+P338: IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.
P317: Get emergency medical help.
WGK Germany 3
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