The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Montelukast 1,2-Diol(Mixture of Diastereomers) , CAS No.186352-97-6
Basic Description Synonyms 186352-97-6 | MONTELUKAST 1,2-DIOL | 1-((((1R)-1-(3-((1E)-2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1,2-dihydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid | UNII-PV596370Q4 | PV596370Q4 | Cyclopropaneacetic acid, 1-((((1R)-1-(3-((1E)-2-( Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Montelukast 1,2-Diol(Mixture of Diastereomers) is a monohydroxylated analog of the leukotriene LTD4 receptor antagonist Montelukast . The isopropyl group of Montelukast is hydroxylated at a terminal carbon to produce Montelukast 1,2-Diol, and this preparation is a mixture of the possible diastereomers of this compound. Montelukast 1,2-Diol is reported to be an antagonist of the LTD4 receptor similar to the parent compound.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(1,2-dihydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid INCHI InChI=1S/C35H36ClNO4S/c1-34(41,22-38)30-8-3-2-6-25(30)12-16-32(42-23-35(17-18-35)21-33(39)40)27-7-4-5-24(19-27)9-14-29-15-11-26-10-13-28(36)20-31(26)37-29/h2-11,13-15,19-20,32,38,41H,12,16-18,21-23H2,1H3,(H,39,40)/b14-9+/t32-,34?/m1/s1 InChi Key UFQIEVSCRCMNLW-SHISVWIYSA-N Canonical SMILES CC(CO)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O Isomeric SMILES CC(CO)(C1=CC=CC=C1CC[C@H](C2=CC=CC(=C2)/C=C/C3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O PubChem CID 9960377 Molecular Weight 602.18
Chemical and Physical Properties Solubility Soluble in acetone, and methanol. Melt Point(°C) 100-109° C
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
