Skip to the beginning of the images gallery

Morpholine - purified by redistillation,≥99.5%, high purity , CAS No.110-91-8

30 Citations

Distillation grade

≥99.5%

CAS#: 110-91-8
Formula: C₄H₉NO
Molecular Weight: 87.12
Beilstein Registry Number: 102549
EC Number: 203-815-1
MDL number: MFCD00005972
PubChem CID: 8083

Item Number

M109058

Grouped product items
SKU	Size	Availability	Price
M109058-25ml	25ml	In stock	$24.90
M109058-100ml	100ml	In stock	$74.90
M109058-500ml	500ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$336.90

Basic Description

Synonyms	C4H9NO \| Drewamine \| NCGC00256942-01 \| J-522715 \| 4-27-00-00015 (Beilstein Handbook Reference) \| Diethyleneimide oxide \| Tetrahydro-1,4-isoxazine \| UNII-8B2ZCK305O \| Tetrahydro-1, 4-isoxazine \| TETRAHYDRO-2H-1, 4-OXAZINE \| Tetrahydro-4H-1-4-oxazine \| AI3-
Specifications & Purity	Distillation grade, ≥99.5%
Storage Temp	Room temperature
Shipped In	Normal
Grade	Distillation grade

Associated Targets(Human)

CYP1B1 Tchem Cytochrome P450 1B1 (0 Activities)

Discover Target: CYP1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A1 Tchem Cytochrome P450 1A1 (0 Activities)

Discover Target: CYP1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1B1 Tchem Cytochrome P450 1B1 (1148 Activities)

Discover Target: CYP1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A1 Tchem Cytochrome P450 1A1 (1169 Activities)

Discover Target: CYP1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	morpholine
INCHI	InChI=1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2
InChi Key	YNAVUWVOSKDBBP-UHFFFAOYSA-N
Canonical SMILES	C1COCCN1
Isomeric SMILES	C1COCCN1
WGK Germany	1
RTECS	QD6475000
PubChem CID	8083
UN Number	2054
Packing Group	I
Molecular Weight	87.12
Beilstein	102549

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number	Certificate Type	Date	Item
G2318906	Certificate of Analysis	Jun 13, 2023	M109058
G2318915	Certificate of Analysis	Jun 13, 2023	M109058
G2318917	Certificate of Analysis	Jun 13, 2023	M109058
K2408081	Certificate of Analysis	Jun 13, 2023	M109058
F2229120	Certificate of Analysis	Jul 05, 2022	M109058
C2303200	Certificate of Analysis	Apr 28, 2022	M109058
E2207146	Certificate of Analysis	Apr 28, 2022	M109058
E2207148	Certificate of Analysis	Apr 28, 2022	M109058
F23061423	Certificate of Analysis	Apr 28, 2022	M109058

Chemical and Physical Properties

Solubility	It is miscible with water and can be miscible with most organic solvents.
Sensitivity	Hygroscopic
Refractive Index	1.4548
Flash Point(°F)	87.8 °F
Flash Point(°C)	35℃
Boil Point(°C)	128.3°C
Melt Point(°C)	-4.76°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS05, GHS02
Signal	Danger
Hazard Statements	H314:Causes severe skin burns and eye damage H302:Harmful if swallowed H312:Harmful in contact with skin H226:Flammable liquid and vapor H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P271:Use only outdoors or in a well-ventilated area. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	1
RTECS	QD6475000
Class	8(3)
Merck Index	6277

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jun-Tao Shi, Xian-Hui Chen, Yuan-Yuan Peng, Gui-Ping Wang, Guang-Yan Du, Quan Li. (2023) Tunable Fluorescence and Morphology of Aggregates Built from a Mechanically Bonded Amphiphilic Bistable [2]Rotaxane. CHEMISTRY-A EUROPEAN JOURNAL, 29 (59): (e202302132). [PMID:37526053] [10.1002/chem.202302132]
2. Ke Wang, Liru An, Ganghui Lu, Jialu Zhang, Zilong Wang, Meiyu Si, Guiyan Liu, Yongfei Zeng. (2023) Effect of heterocyclic substituents on the thermo/pH/CO2-responsiveness of multistimuli-responsive homopolymers. POLYMER, 280 (126039). [PMID:] [10.1016/j.polymer.2023.126039]
3. Qiong Yao, Shouwu Yu. (2023) Preparation and characterisation of a triazine structure charring agent and its application in polypropylene. MATERIALS RESEARCH INNOVATIONS, [PMID:] [10.1080/14328917.2023.2212482]
4. Siyuan Li, Xianrong Yu, Linlin Zeng, Yuhan Xu, Xiaolan Zhao, Wei Tang, Xinrui Duan. (2022) A Sensitive Fluorescent Probe with Large Stokes Shift for Real-Time Tracking Lysosomal pH Changes in Live Cells. ChemistrySelect, 7 (42): (e202202620). [PMID:] [10.1002/slct.202202620]
5. Caiyun Lin, Yuying Li, Weishan Tang, Shufeng Zhou, Xiaoping Rao. (2021) Facile Construction of Bio-Based Supramolecular Hydrogels from Dehydroabietic Acid with a Tricyclic Hydrophenanthrene Skeleton and Stabilized Gel Emulsions. MOLECULES, 26 (21): (6526). [PMID:34770933] [10.3390/molecules26216526]
6. Yingnan Liu, Yaqing Xiao, Minghui Shang, Yuting Zhuang, Li Wang. (2022) Smart fluorescent tag based on amine response for non-contact and visual monitoring of seafood freshness. CHEMICAL ENGINEERING JOURNAL, 428 (132647). [PMID:] [10.1016/j.cej.2021.132647]
7. Jun Mou, Xingqi Fan, Fei Liu, Xiaodan Wang, Tianxiang Zhao, Peng Chen, Ziwei Li, Chunliang Yang, Jianxin Cao. (2021) CO2 hydrogenation to lower olefins over Mn2O3-ZnO/SAPO-34 tandem catalysts. CHEMICAL ENGINEERING JOURNAL, 421 (129978). [PMID:] [10.1016/j.cej.2021.129978]
8. Faming Wang, Pengfei Ren, Katrien V. Bernaerts, Yifu Fu, Wanjun Hu, Naizhen Zhou, Tianzhu Zhang. (2020) Thermoresponsive Poly(2-propyl-2-oxazoline) Surfaces of Glass for Nonenzymatic Cell Harvesting. ACS Applied Bio Materials, 3 (8): (5428–5437). [PMID:35021716] [10.1021/acsabm.0c00650]
9. Shao-Lu Li, Pengfei Wu, Juntao Wang, Jing Wang, Yunxia Hu. (2020) Fabrication of high performance polyamide reverse osmosis membrane from monomer 4-morpholino-m-phenylenediamine and tailoring with zwitterions. DESALINATION, 473 (114169). [PMID:] [10.1016/j.desal.2019.114169]
10. Min Shi, Yanhong Li, Hongtao Cui. (2019) Building homogeneous nanostructure in Ni(OH)2/MWCNTs composite by electrostatic attraction. Micro & Nano Letters, 14 (11): (1151-1156). [PMID:] [10.1049/mnl.2018.5469]
11. Song Wen-tao, Hu Yong-jun, Jin Shan, Li Yu-jian. (2019) Dissociative photoionization of heterocyclic molecule-morpholine under VUV synchrotron radiation. CHINESE JOURNAL OF CHEMICAL PHYSICS, 32 (2): (259-266). [PMID:] [10.1063/1674-0068/cjcp1904068]
12. Yanhong Li, Jing Li, Meiri Wang, Yuanyuan Liu, Hongtao Cui. (2019) High rate performance and stabilized cycle life of Co2+-doped nickel sulfide nanosheets synthesized by a scalable method of solid-state reaction. CHEMICAL ENGINEERING JOURNAL, 366 (33). [PMID:] [10.1016/j.cej.2019.02.066]
13. Xinxin Li, Qingshan Zhao, Xiang Feng, Lei Pan, Zhuangzhuang Wu, Xiaocui Wu, Tianwen Ma, Jialiang Liu, Yuanyuan Pan, Yan Song, Mingbo Wu. (2019) Pyridinic Nitrogen-Doped Graphene Nanoshells Boost the Catalytic Efficiency of Palladium Nanoparticles for the N-Allylation Reaction. ChemSusChem, 12 (4): (858-865). [PMID:30600929] [10.1002/cssc.201802532]
14. Wang Li, Li Jing, Wang Meiri, Liu Yuanyuan, Cui Hongtao. (2019) In situ synthesis of two-dimensional Co2+-doped β-Ni(OH)2 using nickel complex as template for application in supercapacitors. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 89 (2): (492-499). [PMID:] [10.1007/s10971-018-4880-y]
15. Wu Hong, Wang Xianshu, Liu Fei, Cao Jianxin. (2019) Facile in situ hydrothermal crystallization synthesis of SAPO-34/ZSM-5 composite catalyst for methanol to olefin reaction. JOURNAL OF POROUS MATERIALS, 26 (3): (793-802). [PMID:] [10.1007/s10934-018-0676-2]
16. Mengsi Cao, Pingping Zhang, Yanru Feng, Huayin Zhang, Huaijiao Zhu, Kaoqi Lian, Weijun Kang. (2018) Development of a Method for Rapid Determination of Morpholine in Juices and Drugs by Gas Chromatography-Mass Spectrometry. Journal of Analytical Methods in Chemistry, 2018 (9670481). [PMID:29854564] [10.1155/2018/9670481]
17. Huaqi Zhan, Yongjun Hu, Pengchao Wang, Jiaxin Chen. (2017) Molecular structures of gas-phase neutral morpholine and its monohydrated complexes: experimental and theoretical approaches. RSC Advances, 7 (11): (6179-6186). [PMID:] [10.1039/C6RA26582K]
18. Ma Wenle, Feng Yongmei, Wang Li, Xue Junying, Cui Hongtao. (2016) Tailoring the size and electrochemical performance of Mn3O4 nanoparticles by controlling the precipitation process. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 80 (2): (326-332). [PMID:] [10.1007/s10971-016-4107-z]
19. Yapeng Hu, Xiangmei Wang, Juan Li. (2016) Regulating Effect of Exfoliated Clay on Intumescent Char Structure and Flame Retardancy of Polypropylene Composites. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 55 (20): (5892–5901). [PMID:] [10.1021/acs.iecr.6b00480]
20. Wenle Ma, Li Wang, Junying Xue, Hongtao Cui. (2016) Ultra-large scale synthesis of Co–Ni layered double hydroxides monolayer nanosheets by a solvent-free bottom-up strategy. JOURNAL OF ALLOYS AND COMPOUNDS, 662 (315). [PMID:] [10.1016/j.jallcom.2015.12.065]
21. Zhong Zheng, Yihu Song, Huilong Xu, Qiang Zheng. (2015) Thickening of the Immobilized Polymer Layer Using Trace Amount of Amine and Its Role in Promoting Gelation of Colloidal Nanocomposites. MACROMOLECULES, 48 (24): (9015–9023). [PMID:] [10.1021/acs.macromol.5b02004]
22. Ma Wenle, Xue Junying, Cui Hongtao. (2016) New insight on nanostructure assembling of high-performance electrode materials: synthesis of surface-modified hexagonal β-Ni(OH)2 nanosheets as an example. IONICS, 22 (4): (573-579). [PMID:] [10.1007/s11581-015-1570-4]
23. Hongtao Cui, Junying Xue, Wanzhong Ren, Minmin Wang. (2015) Ultra-large scale synthesis of high electrochemical performance SnO2 quantum dots within 5 min at room temperature following a growth self-termination mechanism. JOURNAL OF ALLOYS AND COMPOUNDS, 645 (11). [PMID:] [10.1016/j.jallcom.2015.05.015]
24. Hongtao Cui, Junyin Xue, Minmin Wang. (2015) Synthesis of high electrochemical performance Ni(OH)2 nanosheets through a solvent-free reaction for application in supercapacitor. ADVANCED POWDER TECHNOLOGY, 26 (434). [PMID:] [10.1016/j.apt.2014.11.016]
25. Yan Liu, Zhenhu Cao, Yan Zhang, Zhengping Fang. (2015) Synthesis of zinc N-morpholinomethylphosphonic acid and its application in high density polyethylene. FIRE SAFETY JOURNAL, 71 (1). [PMID:] [10.1016/j.firesaf.2014.11.003]
26. Ming-Hui He, Mei-Lin Su, Zhao-Hui Yu, Guang-Xue Chen, Zhao-Hua Zeng, Jian-Wen Yang. (2015) Benzoylformamides as new photocaged bases for photo-latent anion polymerization. CHINESE CHEMICAL LETTERS, 26 (21). [PMID:] [10.1016/j.cclet.2014.10.002]
27. Minghui He, Shun Jiang, Ruixin Xu, Jianwen Yang, Zhaohua Zeng, Guangxue Chen. (2014) Domino free radical photopolymerization based on phototriggered base proliferation reaction and redox initiation. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 52 (11): (1560-1569). [PMID:] [10.1002/pola.27149]
28. Yan Liu, Zhenhu Cao, Yan Zhang, Zhengping Fang. (2013) Synthesis of Cerium N-Morpholinomethylphosphonic Acid and Its Flame Retardant Application in High Density Polyethylene. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 52 (15): (5334–5340). [PMID:] [10.1021/ie400259f]
29. Min Xie, Guichi Zhu, Yongjun Hu, Huaimin Gu. (2011) Conformations of Morpholine in Liquid and Adsorbed on Gold Nanoparticles Explored by Raman Spectroscopy and Theoretical Calculations. Journal of Physical Chemistry C, 115 (42): (20596–20602). [PMID:] [10.1021/jp206544a]
30. Yan Yan,Pengchong Wang,Ruiying Li,Ying Sun,Rui Zhang,Chuanchuan Huo,Jianfeng Xing,Yalin Dong. (2019-03-13) Synthesis of budesonide conjugates and their anti-inflammatory effects: a preliminary study.. Drug design, development and therapy, 13 (681-694). [PMID:30858698]

References

1. S R el-Shabouri,A F Youssef,F A Mohamed,A M Rageh. (1986-09-01) Colorimetric determination of C-2 unsubstituted phenothiazines, using morpholine and N-bromosuccinimide.. Journal - Association of Official Analytical Chemists, 69 ((5)): (821-824). [PMID:2876980]
2. R V Cooney,P D Ross,G L Bartolini. (1986-07-01) N-nitrosation and N-nitration of morpholine by nitrogen dioxide: inhibition by ascorbate, glutathione and alpha-tocopherol.. Cancer letters, 32 ((1)): (83-90). [PMID:3742490]
3. P Poupin,N Truffaut,B Combourieu,P Besse,M Sancelme,H Veschambre,A M Delort. (1998-01-22) Degradation of morpholine by an environmental Mycobacterium strain involves a cytochrome P-450.. Applied and environmental microbiology, 64 ((1)): (159-165). [PMID:9435074]
4. . (1989-01-01) Morpholine.. IARC monographs on the evaluation of carcinogenic risks to humans, 47 (199-213). [PMID:2699898]
5. B Combourieu,P Besse,M Sancelme,J P Godin,A Monteil,H Veschambre,A M Delort. (2000-08-05) Common degradative pathways of morpholine, thiomorpholine, and piperidine by Mycobacterium aurum MO1: evidence from (1)H-nuclear magnetic resonance and ionspray mass spectrometry performed directly on the incubation medium.. Applied and environmental microbiology, 66 ((8)): (3187-3193). [PMID:10919768]
6. Andrew Parkin,Iain D H Oswald,Simon Parsons. (2004-03-16) Structures of piperazine, piperidine and morpholine.. Acta crystallographica. Section B, Structural science, 60 ((Pt 2)): (219-227). [PMID:15017096]
7. Bram Baert,Eric Deconinck,Mireille Van Gele,Marian Slodicka,Paul Stoppie,Samuel Bodé,Guido Slegers,Yvan Vander Heyden,Jo Lambert,Johan Beetens,Bart De Spiegeleer. (2007-09-11) Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.. Bioorganic & medicinal chemistry, 15 ((22)): (6943-6955). [PMID:17827020]
8. Bruno Bard,Pierre-Alain Carrupt,Sophie Martel. (2009-04-29) Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.. Journal of medicinal chemistry, 52 ((10)): (3416-3419). [PMID:19397318]
9. Radosław Starosta,Barbara Bazanów,Wojciech Barszczewski. (2010-07-10) Chalcogenides of the aminomethylphosphines derived from 1-methylpiperazine, 1-ethylpiperazine and morpholine: NMR, DFT and structural studies for determination of electronic and steric properties of the phosphines.. Dalton transactions (Cambridge, England : 2003), 39 ((32)): (7547-7555). [PMID:20617235]
10. Jan Bornholdt,Jakob Felding,Jesper Langgaard Kristensen. (2010-10-01) Synthesis of enantiopure 3-substituted morpholines.. The Journal of organic chemistry, 75 ((21)): (7454-7457). [PMID:20879782]
11. Angeliki P Kourounakis,Alexios N Matralis,Anastasios Nikitakis. (2010-10-05) Design of more potent squalene synthase inhibitors with multiple activities.. Bioorganic & medicinal chemistry, 18 ((21)): (7402-7412). [PMID:20888243]
12. Su-Juan Li,Jing Li,Kang Wang,Chen Wang,Jing-Juan Xu,Hong-Yuan Chen,Xing-Hua Xia,Qun Huo. (2010-10-21) A nanochannel array-based electrochemical device for quantitative label-free DNA analysis.. ACS nano, 4 ((11)): (6417-6424). [PMID:20958077]
13. Guozheng Liu,Shuping Dou,Yuxia Liu,Minmin Liang,Ling Chen,Dengfeng Cheng,Dale Greiner,Mary Rusckowski,Donald J Hnatowich. (2011-02-15) Unexpected side products in the conjugation of an amine-derivatized morpholino oligomer with p-isothiocyanate benzyl DTPA and their removal.. Nuclear medicine and biology, 38 ((2)): (159-163). [PMID:21315270]
14. Stephen D Ramgren,Amanda L Silberstein,Yang Yang,Neil K Garg. (2011-02-24) Nickel-catalyzed amination of aryl sulfamates.. Angewandte Chemie (International ed. in English), 50 ((9)): (2171-2173). [PMID:21344578]
15. Saleh Ihmaid,Jasim Al-Rawi,Christopher Bradley,Michael J Angove,Murray N Robertson,Rachel L Clark. (2011-06-15) Synthesis, structural elucidation, DNA-PK inhibition, homology modelling and anti-platelet activity of morpholino-substituted-1,3-naphth-oxazines.. Bioorganic & medicinal chemistry, 19 ((13)): (3983-3994). [PMID:21664823]
16. Y Suman Reddy,A P John Pal,Preeti Gupta,Alafia A Ansari,Yashwant D Vankar. (2011-06-18) Ceric ammonium nitrate-catalyzed azidation of 1,2-anhydro sugars: application in the synthesis of structurally diverse sugar-derived morpholine 1,2,3-triazoles and 1,4-oxazin-2-ones.. The Journal of organic chemistry, 76 ((15)): (5972-5984). [PMID:21679000]
17. Shi-Kai Xiang,Bo Zhang,Li-He Zhang,Yuxin Cui,Ning Jiao. (2011-06-21) Morpholine catalyzed direct C3 alkenylation of indoles with α,β-unsaturated aldehydes.. Chemical communications (Cambridge, England), 47 ((28)): (8097-8099). [PMID:21687862]
18. A Olma,A Lasota,A Kudaj. (2011-08-19) A convenient route to optically pure α-alkyl-β-(sec-amino)alanines.. Amino acids, 42 ((6)): (2525-2528). [PMID:21847610]
19. William C Silvers,Alex S Payne,Robin L McCarley. (2011-09-20) Shedding light by cancer redox-human NAD(P)H:quinone oxidoreductase 1 activation of a cloaked fluorescent dye.. Chemical communications (Cambridge, England), 47 ((40)): (11264-11266). [PMID:21927746]
20. Ruina Gao,Liang Li,Cen Xie,Xingxing Diao,Dafang Zhong,Xiaoyan Chen. (2011-12-21) Metabolism and pharmacokinetics of morinidazole in humans: identification of diastereoisomeric morpholine N+-glucuronides catalyzed by UDP glucuronosyltransferase 1A9.. Drug metabolism and disposition: the biological fate of chemicals, 40 ((3)): (556-567). [PMID:22184458]
21. J Luong,R A Shellie,H Cortes,R Gras,T Hayward. (2012-02-14) Ultra-trace level analysis of morpholine, cyclohexylamine, and diethylaminoethanol in steam condensate by gas chromatography with multi-mode inlet, and flame ionization detection.. Journal of chromatography. A, 1229 (223-229). [PMID:22325017]
22. Andrew J Tilley,Shannon D Zanatta,Cheng Xue Qin,In-Kyeom Kim,Young-Mi Seok,Alastair Stewart,Owen L Woodman,Spencer J Williams. (2012-03-02) 2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition.. Bioorganic & medicinal chemistry, 20 ((7)): (2353-2361). [PMID:22377671]
23. Jennifer Bonner,Michael Letko,Oliver Brant Nikolaus,Lisa Krug,Alexandria Cooper,Benjamin Chadwick,Phoebe Conklin,Amy Lim,Chi-Bin Chien,Richard I Dorsky. (2012-06-08) Midline crossing is not required for subsequent pathfinding decisions in commissural neurons.. Neural development, 7 (18-18). [PMID:22672767]
24. Jason N Mock,John P Taliaferro,Xiao Lu,Sravan Kumar Patel,Brian S Cummings,Timothy E Long. (2012-06-09) Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer.. Bioorganic & medicinal chemistry letters, 22 ((14)): (4854-4858). [PMID:22677312]
25. Bachir Latli,Matt Hrapchak,Jon C Lorenz,Carl A Busacca,Chris Senanayake. (2012-06-26) Synthesis of a potent cathepsin s inhibitor labeled with deuterium and carbon-14.. Current radiopharmaceuticals, 5 ((4)): (314-317). [PMID:22724423]
26. Mohammednoor Altarawneh,Bogdan Z Dlugogorski. (2012-07-04) A mechanistic and kinetic study on the decomposition of morpholine.. The journal of physical chemistry. A, 116 ((29)): (7703-7711). [PMID:22746995]
27. Amjad M Qandil,Noor M Jamhawi,Bassam M Tashtoush,Ahmad M Al-Ajlouni,Nasir M Idkaidek,Aiman A Obaidat. (2012-09-22) The hydrolysis kinetics of monobasic and dibasic aminoalkyl esters of ketorolac.. Drug development and industrial pharmacy, 39 ((9)): (1346-1356). [PMID:22995063]
28. Mark E Wood,Sabine Bissiriou,Christopher Lowe,Kim M Windeatt. (2013-03-13) Synthetic use of the primary kinetic isotope effect in hydrogen atom transfer 2: generation of captodatively stabilised radicals.. Organic & biomolecular chemistry, 11 ((16)): (2712-2723). [PMID:23479029]
29. Louis De Muynck,Sarah Herdewyn,Sander Beel,Wendy Scheveneels,Ludo Van Den Bosch,Wim Robberecht,Philip Van Damme. (2013-05-28) The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding.. Neurobiology of aging, 34 ((11)): (2541-2547). [PMID:23706646]
30. Andrea C Mislak,Kathleen M Frey,Mariela Bollini,William L Jorgensen,Karen S Anderson. (2014-04-15) A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase.. Biochimica et biophysica acta, 1840 ((7)): (2203-2211). [PMID:24726448]
31. Claire L Jarvis,Matthew T Richers,Martin Breugst,K N Houk,Daniel Seidel. (2014-06-14) Redox-neutral α-sulfenylation of secondary amines: ring-fused N,S-acetals.. Organic letters, 16 ((13)): (3556-3559). [PMID:24927364]
32. Benoît Pilmis,Vincent Jullien,Jack Sobel,Marc Lecuit,Olivier Lortholary,Caroline Charlier. (2014-09-11) Antifungal drugs during pregnancy: an updated review.. The Journal of antimicrobial chemotherapy, 70 ((1)): (14-22). [PMID:25204341]
33. Anantha-Barathi Muthukrishnan,Antti Martikainen,Ramakanth Neeli-Venkata,Andre S Ribeiro. (2014-10-01) In vivo transcription kinetics of a synthetic gene uninvolved in stress-response pathways in stressed Escherichia coli cells.. PloS one, 9 ((9)): (e109005-e109005). [PMID:25268540]
34. Kyeong-Ah Jung,Bo-Hyun Choi,Mi-Kyoung Kwak. (2014-12-24) The c-MET/PI3K signaling is associated with cancer resistance to doxorubicin and photodynamic therapy by elevating BCRP/ABCG2 expression.. Molecular pharmacology, 87 ((3)): (465-476). [PMID:25534417]
35. Vítor S Fernandes,Wenkuan Xin,Georgi V Petkov. (2015-05-08) Novel mechanism of hydrogen sulfide-induced guinea pig urinary bladder smooth muscle contraction: role of BK channels and cholinergic neurotransmission.. American journal of physiology. Cell physiology, 309 ((2)): (C107-C116). [PMID:25948731]
36. Avinash Bhadani,Misako Tani,Takeshi Endo,Kenichi Sakai,Masahiko Abe,Hideki Sakai. (2015-07-07) New ester based gemini surfactants: the effect of different cationic headgroups on micellization properties and viscosity of aqueous micellar solution.. Physical chemistry chemical physics : PCCP, 17 ((29)): (19474-19483). [PMID:26145125]
37. Laura A Ciolino. (2015-07-16) Quantitation of Synthetic Cannabinoids in Plant Materials Using High Performance Liquid Chromatography with UV Detection (Validated Method).. Journal of forensic sciences, 60 ((5)): (1171-1181). [PMID:26175160]
38. Xing Liu,Yuanfu Lu,Xinfu Guan,Bingning Dong,Hemantkumar Chavan,Jin Wang,Yiqing Zhang,Partha Krishnamurthy,Feng Li. (2015-07-28) Metabolomics reveals the formation of aldehydes and iminium in gefitinib metabolism.. Biochemical pharmacology, 97 ((1)): (111-121). [PMID:26212543]
39. Alfonso Pérez-Gallardo,Blanca García-Almendárez,Gustavo Barbosa-Cánovas,Diana Pimentel-González,L R Reyes-González,Carlos Regalado. (2015-09-08) Effect of starch-beeswax coatings on quality parameters of blackberries (Rubus spp.).. Journal of food science and technology, 52 ((9)): (5601-5610). [PMID:26344973]
40. Er Bei,Xiao Li,Fuhua Wu,Shixiang Li,Xinsheng He,Yufang Wang,Yu Qiu,Yu Wang,Chengkun Wang,Jun Wang,Xiaojian Zhang,Chao Chen. (2020-07-06) Formation of N-nitrosodimethylamine precursors through the microbiological metabolism of nitrogenous substrates in water.. Water research, 183 (116055-116055). [PMID:32622235]
41. Andrea Trabocchi,Irene Stefanini,Manfredi Morvillo,Leonardo Ciofi,Duccio Cavalieri,Antonio Guarna. (2010-10-16) Chemical genetics approach to identify new small molecule modulators of cell growth by phenotypic screening of Saccharomyces cerevisiae strains with a library of morpholine-derived compounds.. Organic & biomolecular chemistry, 8 ((24)): (5552-5557). [PMID:20949215]
42. Linda Z Holland,Takayuki Onai. (2011-08-02) Analyses of gene function in amphioxus embryos by microinjection of mRNAs and morpholino oligonucleotides.. Methods in molecular biology (Clifton, N.J.), 770 (423-438). [PMID:21805274]
43. Sean E Low,Ian G Woods,Mathieu Lachance,Joel Ryan,Alexander F Schier,Louis Saint-Amant. (2012-04-12) Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b.. Journal of neurophysiology, 108 ((1)): (148-159). [PMID:22490555]
44. R John Xavier,S Ashok Raj. (2012-10-27) Ab initio, density functional computations, FT-IR, FT-Raman and molecular geometry of 4-morpholine carbonitrile.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101 (148-155). [PMID:23099173]
45. Ryan C Middleton,Eric A Shelden. (2013-01-15) Small heat shock protein HSPB1 regulates growth of embryonic zebrafish craniofacial muscles.. Experimental cell research, 319 ((6)): (860-874). [PMID:23313812]
46. Jun-Tao Shi, Xian-Hui Chen, Yuan-Yuan Peng, Gui-Ping Wang, Guang-Yan Du, Quan Li. (2023) Tunable Fluorescence and Morphology of Aggregates Built from a Mechanically Bonded Amphiphilic Bistable [2]Rotaxane. CHEMISTRY-A EUROPEAN JOURNAL, 29 (59): (e202302132). [PMID:37526053] [10.1002/chem.202302132]
47. Ke Wang, Liru An, Ganghui Lu, Jialu Zhang, Zilong Wang, Meiyu Si, Guiyan Liu, Yongfei Zeng. (2023) Effect of heterocyclic substituents on the thermo/pH/CO2-responsiveness of multistimuli-responsive homopolymers. POLYMER, 280 (126039). [PMID:] [10.1016/j.polymer.2023.126039]
48. Qiong Yao, Shouwu Yu. (2023) Preparation and characterisation of a triazine structure charring agent and its application in polypropylene. MATERIALS RESEARCH INNOVATIONS, [PMID:] [10.1080/14328917.2023.2212482]
49. Siyuan Li, Xianrong Yu, Linlin Zeng, Yuhan Xu, Xiaolan Zhao, Wei Tang, Xinrui Duan. (2022) A Sensitive Fluorescent Probe with Large Stokes Shift for Real-Time Tracking Lysosomal pH Changes in Live Cells. ChemistrySelect, 7 (42): (e202202620). [PMID:] [10.1002/slct.202202620]
50. Caiyun Lin, Yuying Li, Weishan Tang, Shufeng Zhou, Xiaoping Rao. (2021) Facile Construction of Bio-Based Supramolecular Hydrogels from Dehydroabietic Acid with a Tricyclic Hydrophenanthrene Skeleton and Stabilized Gel Emulsions. MOLECULES, 26 (21): (6526). [PMID:34770933] [10.3390/molecules26216526]
51. Yingnan Liu, Yaqing Xiao, Minghui Shang, Yuting Zhuang, Li Wang. (2022) Smart fluorescent tag based on amine response for non-contact and visual monitoring of seafood freshness. CHEMICAL ENGINEERING JOURNAL, 428 (132647). [PMID:] [10.1016/j.cej.2021.132647]
52. Jun Mou, Xingqi Fan, Fei Liu, Xiaodan Wang, Tianxiang Zhao, Peng Chen, Ziwei Li, Chunliang Yang, Jianxin Cao. (2021) CO2 hydrogenation to lower olefins over Mn2O3-ZnO/SAPO-34 tandem catalysts. CHEMICAL ENGINEERING JOURNAL, 421 (129978). [PMID:] [10.1016/j.cej.2021.129978]
53. Faming Wang, Pengfei Ren, Katrien V. Bernaerts, Yifu Fu, Wanjun Hu, Naizhen Zhou, Tianzhu Zhang. (2020) Thermoresponsive Poly(2-propyl-2-oxazoline) Surfaces of Glass for Nonenzymatic Cell Harvesting. ACS Applied Bio Materials, 3 (8): (5428–5437). [PMID:35021716] [10.1021/acsabm.0c00650]
54. Shao-Lu Li, Pengfei Wu, Juntao Wang, Jing Wang, Yunxia Hu. (2020) Fabrication of high performance polyamide reverse osmosis membrane from monomer 4-morpholino-m-phenylenediamine and tailoring with zwitterions. DESALINATION, 473 (114169). [PMID:] [10.1016/j.desal.2019.114169]
55. Min Shi, Yanhong Li, Hongtao Cui. (2019) Building homogeneous nanostructure in Ni(OH)2/MWCNTs composite by electrostatic attraction. Micro & Nano Letters, 14 (11): (1151-1156). [PMID:] [10.1049/mnl.2018.5469]
56. Song Wen-tao, Hu Yong-jun, Jin Shan, Li Yu-jian. (2019) Dissociative photoionization of heterocyclic molecule-morpholine under VUV synchrotron radiation. CHINESE JOURNAL OF CHEMICAL PHYSICS, 32 (2): (259-266). [PMID:] [10.1063/1674-0068/cjcp1904068]
57. Yanhong Li, Jing Li, Meiri Wang, Yuanyuan Liu, Hongtao Cui. (2019) High rate performance and stabilized cycle life of Co2+-doped nickel sulfide nanosheets synthesized by a scalable method of solid-state reaction. CHEMICAL ENGINEERING JOURNAL, 366 (33). [PMID:] [10.1016/j.cej.2019.02.066]
58. Xinxin Li, Qingshan Zhao, Xiang Feng, Lei Pan, Zhuangzhuang Wu, Xiaocui Wu, Tianwen Ma, Jialiang Liu, Yuanyuan Pan, Yan Song, Mingbo Wu. (2019) Pyridinic Nitrogen-Doped Graphene Nanoshells Boost the Catalytic Efficiency of Palladium Nanoparticles for the N-Allylation Reaction. ChemSusChem, 12 (4): (858-865). [PMID:30600929] [10.1002/cssc.201802532]
59. Wang Li, Li Jing, Wang Meiri, Liu Yuanyuan, Cui Hongtao. (2019) In situ synthesis of two-dimensional Co2+-doped β-Ni(OH)2 using nickel complex as template for application in supercapacitors. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 89 (2): (492-499). [PMID:] [10.1007/s10971-018-4880-y]
60. Wu Hong, Wang Xianshu, Liu Fei, Cao Jianxin. (2019) Facile in situ hydrothermal crystallization synthesis of SAPO-34/ZSM-5 composite catalyst for methanol to olefin reaction. JOURNAL OF POROUS MATERIALS, 26 (3): (793-802). [PMID:] [10.1007/s10934-018-0676-2]
61. Mengsi Cao, Pingping Zhang, Yanru Feng, Huayin Zhang, Huaijiao Zhu, Kaoqi Lian, Weijun Kang. (2018) Development of a Method for Rapid Determination of Morpholine in Juices and Drugs by Gas Chromatography-Mass Spectrometry. Journal of Analytical Methods in Chemistry, 2018 (9670481). [PMID:29854564] [10.1155/2018/9670481]
62. Huaqi Zhan, Yongjun Hu, Pengchao Wang, Jiaxin Chen. (2017) Molecular structures of gas-phase neutral morpholine and its monohydrated complexes: experimental and theoretical approaches. RSC Advances, 7 (11): (6179-6186). [PMID:] [10.1039/C6RA26582K]
63. Ma Wenle, Feng Yongmei, Wang Li, Xue Junying, Cui Hongtao. (2016) Tailoring the size and electrochemical performance of Mn3O4 nanoparticles by controlling the precipitation process. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 80 (2): (326-332). [PMID:] [10.1007/s10971-016-4107-z]
64. Yapeng Hu, Xiangmei Wang, Juan Li. (2016) Regulating Effect of Exfoliated Clay on Intumescent Char Structure and Flame Retardancy of Polypropylene Composites. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 55 (20): (5892–5901). [PMID:] [10.1021/acs.iecr.6b00480]
65. Wenle Ma, Li Wang, Junying Xue, Hongtao Cui. (2016) Ultra-large scale synthesis of Co–Ni layered double hydroxides monolayer nanosheets by a solvent-free bottom-up strategy. JOURNAL OF ALLOYS AND COMPOUNDS, 662 (315). [PMID:] [10.1016/j.jallcom.2015.12.065]
66. Zhong Zheng, Yihu Song, Huilong Xu, Qiang Zheng. (2015) Thickening of the Immobilized Polymer Layer Using Trace Amount of Amine and Its Role in Promoting Gelation of Colloidal Nanocomposites. MACROMOLECULES, 48 (24): (9015–9023). [PMID:] [10.1021/acs.macromol.5b02004]
67. Ma Wenle, Xue Junying, Cui Hongtao. (2016) New insight on nanostructure assembling of high-performance electrode materials: synthesis of surface-modified hexagonal β-Ni(OH)2 nanosheets as an example. IONICS, 22 (4): (573-579). [PMID:] [10.1007/s11581-015-1570-4]
68. Hongtao Cui, Junying Xue, Wanzhong Ren, Minmin Wang. (2015) Ultra-large scale synthesis of high electrochemical performance SnO2 quantum dots within 5 min at room temperature following a growth self-termination mechanism. JOURNAL OF ALLOYS AND COMPOUNDS, 645 (11). [PMID:] [10.1016/j.jallcom.2015.05.015]
69. Hongtao Cui, Junyin Xue, Minmin Wang. (2015) Synthesis of high electrochemical performance Ni(OH)2 nanosheets through a solvent-free reaction for application in supercapacitor. ADVANCED POWDER TECHNOLOGY, 26 (434). [PMID:] [10.1016/j.apt.2014.11.016]
70. Yan Liu, Zhenhu Cao, Yan Zhang, Zhengping Fang. (2015) Synthesis of zinc N-morpholinomethylphosphonic acid and its application in high density polyethylene. FIRE SAFETY JOURNAL, 71 (1). [PMID:] [10.1016/j.firesaf.2014.11.003]
71. Ming-Hui He, Mei-Lin Su, Zhao-Hui Yu, Guang-Xue Chen, Zhao-Hua Zeng, Jian-Wen Yang. (2015) Benzoylformamides as new photocaged bases for photo-latent anion polymerization. CHINESE CHEMICAL LETTERS, 26 (21). [PMID:] [10.1016/j.cclet.2014.10.002]
72. Minghui He, Shun Jiang, Ruixin Xu, Jianwen Yang, Zhaohua Zeng, Guangxue Chen. (2014) Domino free radical photopolymerization based on phototriggered base proliferation reaction and redox initiation. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 52 (11): (1560-1569). [PMID:] [10.1002/pola.27149]
73. Yan Liu, Zhenhu Cao, Yan Zhang, Zhengping Fang. (2013) Synthesis of Cerium N-Morpholinomethylphosphonic Acid and Its Flame Retardant Application in High Density Polyethylene. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 52 (15): (5334–5340). [PMID:] [10.1021/ie400259f]
74. Min Xie, Guichi Zhu, Yongjun Hu, Huaimin Gu. (2011) Conformations of Morpholine in Liquid and Adsorbed on Gold Nanoparticles Explored by Raman Spectroscopy and Theoretical Calculations. Journal of Physical Chemistry C, 115 (42): (20596–20602). [PMID:] [10.1021/jp206544a]
75. Yan Yan,Pengchong Wang,Ruiying Li,Ying Sun,Rui Zhang,Chuanchuan Huo,Jianfeng Xing,Yalin Dong. (2019-03-13) Synthesis of budesonide conjugates and their anti-inflammatory effects: a preliminary study.. Drug design, development and therapy, 13 (681-694). [PMID:30858698]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.