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Morpholine - purified by redistillation,≥99.5%, high purity , CAS No.110-91-8

Distillation grade

≥99.5%

CAS#: 110-91-8
Formula: C₄H₉NO
Molecular Weight: 87.12
Beilstein Registry Number: 102549
EC Number: 203-815-1
MDL number: MFCD00005972
PubChem CID: 8083

Item Number

M109058

Grouped product items
SKU	Size	Availability	Price
M109058-25ml	25ml	In stock	$24.90
M109058-100ml	100ml	In stock	$74.90
M109058-500ml	500ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$336.90

Basic Description

Synonyms	MORPHOLINE \| 110-91-8 \| 1-Oxa-4-azacyclohexane \| Diethylene oximide \| Tetrahydro-1,4-oxazine \| Diethylenimide oxide \| Diethyleneimide oxide \| Diethylene imidoxide \| Drewamine \| Tetrahydro-2H-1,4-oxazine \| Tetrahydro-p-oxazine \| p-Isoxazine, tetrahydro- \| morpholin \| Tetrahydro-1,4
Specifications & Purity	Distillation grade, ≥99.5%
Storage Temp	Room temperature
Shipped In	Normal
Grade	Distillation grade

Associated Targets(Human)

CYP1B1 Tchem Cytochrome P450 1B1 0 Activities

Discover Target: CYP1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A1 Tchem Cytochrome P450 1A1 0 Activities

Discover Target: CYP1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Cytochrome P450 1B1 1148 Activities

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cytochrome P450 1A1 1169 Activities

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Skin 286 Activities

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Names and Identifiers

IUPAC Name	morpholine
INCHI	InChI=1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2
InChi Key	YNAVUWVOSKDBBP-UHFFFAOYSA-N
Canonical SMILES	C1COCCN1
Isomeric SMILES	C1COCCN1
WGK Germany	1
RTECS	QD6475000
PubChem CID	8083
UN Number	2054
Packing Group	I
Molecular Weight	87.12
Beilstein	102549

Certificates

Certificate of Analysis(COA)

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8 results found

Lot Number	Certificate Type	Date	Item
G2318906	Certificate of Analysis	Jun 13, 2023	M109058
G2318915	Certificate of Analysis	Jun 13, 2023	M109058
G2318917	Certificate of Analysis	Jun 13, 2023	M109058
F2229120	Certificate of Analysis	Jul 05, 2022	M109058
C2303200	Certificate of Analysis	Apr 28, 2022	M109058
E2207146	Certificate of Analysis	Apr 28, 2022	M109058
E2207148	Certificate of Analysis	Apr 28, 2022	M109058
F23061423	Certificate of Analysis	Apr 28, 2022	M109058

Chemical and Physical Properties

Solubility	It is miscible with water and can be miscible with most organic solvents.
Sensitivity	Hygroscopic
Refractive Index	1.4548
Flash Point(°F)	87.8 °F
Flash Point(°C)	35℃
Boil Point(°C)	128.3°C
Melt Point(°C)	-4.76°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS05, GHS02
Signal	Danger
Hazard Statements	H314:Causes severe skin burns and eye damage H302:Harmful if swallowed H312:Harmful in contact with skin H226:Flammable liquid and vapor H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P271:Use only outdoors or in a well-ventilated area. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	1
RTECS	QD6475000
Class	8(3)
Merck Index	6277

Citations of This Product

1. Jun-Tao Shi, Xian-Hui Chen, Yuan-Yuan Peng, Gui-Ping Wang, Guang-Yan Du, Quan Li. (2023) Tunable Fluorescence and Morphology of Aggregates Built from a Mechanically Bonded Amphiphilic Bistable [2]Rotaxane. CHEMISTRY-A EUROPEAN JOURNAL, 29 (59): (e202302132). [PMID:37526053]
2. Ke Wang, Liru An, Ganghui Lu, Jialu Zhang, Zilong Wang, Meiyu Si, Guiyan Liu, Yongfei Zeng. (2023) Effect of heterocyclic substituents on the thermo/pH/CO2-responsiveness of multistimuli-responsive homopolymers. POLYMER, 280 (126039). [PMID:]
3. Qiong Yao, Shouwu Yu. (2023) Preparation and characterisation of a triazine structure charring agent and its application in polypropylene. MATERIALS RESEARCH INNOVATIONS, [PMID:]
4. Siyuan Li, Xianrong Yu, Linlin Zeng, Yuhan Xu, Xiaolan Zhao, Wei Tang, Xinrui Duan. (2022) A Sensitive Fluorescent Probe with Large Stokes Shift for Real-Time Tracking Lysosomal pH Changes in Live Cells. ChemistrySelect, 7 (42): (e202202620). [PMID:]
5. Caiyun Lin, Yuying Li, Weishan Tang, Shufeng Zhou, Xiaoping Rao. (2021) Facile Construction of Bio-Based Supramolecular Hydrogels from Dehydroabietic Acid with a Tricyclic Hydrophenanthrene Skeleton and Stabilized Gel Emulsions. MOLECULES, 26 (21): (6526). [PMID:34770933]
6. Yan Yan,Pengchong Wang,Ruiying Li,Ying Sun,Rui Zhang,Chuanchuan Huo,Jianfeng Xing,Yalin Dong. (2019-03-13) Synthesis of budesonide conjugates and their anti-inflammatory effects: a preliminary study.. Drug design, development and therapy, 13 (681-694). [PMID:30858698]

References

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23. Jason N Mock,John P Taliaferro,Xiao Lu,Sravan Kumar Patel,Brian S Cummings,Timothy E Long. (2012-06-09) Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer.. Bioorganic & medicinal chemistry letters, 22 ((14)): (4854-4858). [PMID:22677312]
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47. Ke Wang, Liru An, Ganghui Lu, Jialu Zhang, Zilong Wang, Meiyu Si, Guiyan Liu, Yongfei Zeng. (2023) Effect of heterocyclic substituents on the thermo/pH/CO2-responsiveness of multistimuli-responsive homopolymers. POLYMER, 280 (126039). [PMID:]
48. Qiong Yao, Shouwu Yu. (2023) Preparation and characterisation of a triazine structure charring agent and its application in polypropylene. MATERIALS RESEARCH INNOVATIONS, [PMID:]
49. Siyuan Li, Xianrong Yu, Linlin Zeng, Yuhan Xu, Xiaolan Zhao, Wei Tang, Xinrui Duan. (2022) A Sensitive Fluorescent Probe with Large Stokes Shift for Real-Time Tracking Lysosomal pH Changes in Live Cells. ChemistrySelect, 7 (42): (e202202620). [PMID:]
50. Caiyun Lin, Yuying Li, Weishan Tang, Shufeng Zhou, Xiaoping Rao. (2021) Facile Construction of Bio-Based Supramolecular Hydrogels from Dehydroabietic Acid with a Tricyclic Hydrophenanthrene Skeleton and Stabilized Gel Emulsions. MOLECULES, 26 (21): (6526). [PMID:34770933]
51. Yan Yan,Pengchong Wang,Ruiying Li,Ying Sun,Rui Zhang,Chuanchuan Huo,Jianfeng Xing,Yalin Dong. (2019-03-13) Synthesis of budesonide conjugates and their anti-inflammatory effects: a preliminary study.. Drug design, development and therapy, 13 (681-694). [PMID:30858698]

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