Moxifloxacin HCl - ≥99%, high purity , Bacterial DNA gyrase inhibitor, CAS No.186826-86-8, Bacterial DNA gyrase inhibitor

  • ≥99%
Item Number
M129861
Grouped product items
SKUSizeAvailabilityPrice Qty
M129861-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$64.90
M129861-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$103.90
M129861-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$234.90
M129861-1g
1g
In stock
$423.90
M129861-5g
5g
In stock
$1,903.90
M129861-25g
25g
In stock
$8,565.90

Basic Description

Synonyms1-Cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylicacidhydrochloride | MOXIFLOXACIN HCL [VANDF] | Q368941 | 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-met
Specifications & Purity≥99%
Biochemical and Physiological MechanismsMoxifloxacin Hydrochloride is the hydrochloride salt preparation of Moxifloxacin, an 8-methoxy-fluoroquinone compound with broad-spectrum bactericidal activity against gram-positive and gram-negative strains. 8-methoxy-fluoroquinones are described to inhi
Storage TempStore at 2-8°C
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionBacterial DNA gyrase inhibitor
Product Description

Moxifloxacin is a fourth-generation synthetic fluoroquinolone antibacterial agent.
An antibacterial agent that inhibits the activities of Topo II (DNA gyrase) and topoisomerase IV.

Associated Targets(Human)

SMPD1 Tchem Sphingomyelin phosphodiesterase (13561 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC4 Tchem Multidrug resistance-associated protein 4 (785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Galc Galactocerebrosidase (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus (3973 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus sp. 'group A' (3417 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ska Streptokinase A (5805 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid;hydrochloride
INCHI InChI=1S/C21H24FN3O4.ClH/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24;/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28);1H/t11-,16+;/m0./s1
InChi Key IDIIJJHBXUESQI-DFIJPDEKSA-N
Canonical SMILES COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl
Isomeric SMILES COC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl
RTECS VB1983750
Alternate CAS 151096-09-2
PubChem CID 101526
Molecular Weight 437.89
Beilstein 8377447

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate TypeDateItem
E2217145Certificate of AnalysisMar 19, 2024 M129861
E2217151Certificate of AnalysisMar 19, 2024 M129861
E2217163Certificate of AnalysisMar 19, 2024 M129861
C2113101Certificate of AnalysisAug 16, 2023 M129861
C2113102Certificate of AnalysisAug 16, 2023 M129861
H1920120Certificate of AnalysisMar 07, 2023 M129861
C2115011Certificate of AnalysisDec 15, 2022 M129861
C2115012Certificate of AnalysisDec 15, 2022 M129861
K2025230Certificate of AnalysisSep 19, 2022 M129861
D1503032Certificate of AnalysisSep 19, 2022 M129861
A2416073Certificate of AnalysisMar 14, 2022 M129861
C2115013Certificate of AnalysisFeb 16, 2022 M129861

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Chemical and Physical Properties

SolubilitySoluble in water (24 mg/ml), DMSO (88 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).
Melt Point(°C)323.9-325°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H412:Harmful to aquatic life with long lasting effects

H302:Harmful if swallowed

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

RTECS VB1983750

Related Documents

Citations of This Product

1. Ayesha Younas, Zhuolin Dong, Ziye Hou, Muhammad Asad, Mengru Li, Nan Zhang.  (2023)  A chitosan/fucoidan nanoparticle-loaded pullulan microneedle patch for differential drug release to promote wound healing.  CARBOHYDRATE POLYMERS,  306  (120593).  [PMID:36746584]
2. Fan Mo, Yi Liu, Yingyin Xu, Qingsen He, Pengfei Sun, Xiaoping Dong.  (2022)  Photocatalytic elimination of moxifloxacin by two-dimensional graphitic carbon nitride nanosheets: Enhanced activity, degradation mechanism and potential practical application.  SEPARATION AND PURIFICATION TECHNOLOGY,  292  (121067).  [PMID:]

References

1. Ayesha Younas, Zhuolin Dong, Ziye Hou, Muhammad Asad, Mengru Li, Nan Zhang.  (2023)  A chitosan/fucoidan nanoparticle-loaded pullulan microneedle patch for differential drug release to promote wound healing.  CARBOHYDRATE POLYMERS,  306  (120593).  [PMID:36746584]
2. Fan Mo, Yi Liu, Yingyin Xu, Qingsen He, Pengfei Sun, Xiaoping Dong.  (2022)  Photocatalytic elimination of moxifloxacin by two-dimensional graphitic carbon nitride nanosheets: Enhanced activity, degradation mechanism and potential practical application.  SEPARATION AND PURIFICATION TECHNOLOGY,  292  (121067).  [PMID:]

Solution Calculators