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MPI-5a - 98%, high purity , CAS No.1259296-46-2

≥98%

CAS#: 1259296-46-2
Formula: C₁₆H₁₇N₃O₃
Molecular Weight: 299.32
PubChem CID: 49831258

Item Number

M412352

Grouped product items
SKU	Size	Availability	Price
M412352-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$998.90
M412352-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$189.90
M412352-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,495.90
M412352-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$669.90
M412352-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$939.90

View related series

HDAC6 Inhibitor

Basic Description

Synonyms	1,2,3,4-tetrahydro-N-hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-6-isoquinolinecarboxamide \| MPI_5a \| Histone Deacetylase 6
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	MPI-5a is a potent and selective inhibitor of HDAC6 with IC50 of 36 nM. MPI-5a inhibits acyl-tubulin accumulation in cells with IC50 of 210 nM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information MPI-5a is a potent and selective inhibitor of HDAC6 with IC50 of 36 nM. MPI-5a inhibits acyl-tubulin accumulation in cells with IC50 of 210 nM.

Associated Targets(Human)

HDAC6 Tclin Histone deacetylase 6 (4 Activities)

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC8 Tclin Histone deacetylase 8 (4516 Activities)

Discover Target: HDAC8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HDAC10 Tclin Histone deacetylase 10 (801 Activities)

Discover Target: HDAC10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HDAC2 Tclin Histone deacetylase 2 (3971 Activities)

Discover Target: HDAC2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HDAC3 Tclin Histone deacetylase 3 (3654 Activities)

Discover Target: HDAC3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HDAC4 Tclin Histone deacetylase 4 (2328 Activities)

Discover Target: HDAC4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HDAC11 Tclin Histone deacetylase 11 (967 Activities)

Discover Target: HDAC11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HDAC7 Tclin Histone deacetylase 7 (1047 Activities)

Discover Target: HDAC7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP17 Tchem Matrix metalloproteinase 17 (28 Activities)

Discover Target: MMP17

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Caco-2 (12174 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mmp2 Matrix metalloproteinase-2 (12 Activities)

Discover Target: Mmp2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac1 Histone deacetylase 1 (93 Activities)

Discover Target: Hdac1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac5 Histone deacetylase 5 (5 Activities)

Discover Target: Hdac5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp9 Matrix metalloproteinase 9 (38 Activities)

Discover Target: Mmp9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamide
INCHI	InChI=1S/C16H17N3O3/c1-18-7-2-3-14(18)16(21)19-8-6-11-9-12(15(20)17-22)4-5-13(11)10-19/h2-5,7,9,22H,6,8,10H2,1H3,(H,17,20)
InChi Key	NNQAQGDSGCGFER-UHFFFAOYSA-N
Canonical SMILES	CN1C=CC=C1C(=O)N2CCC3=C(C2)C=CC(=C3)C(=O)NO
Isomeric SMILES	CN1C=CC=C1C(=O)N2CCC3=C(C2)C=CC(=C3)C(=O)NO
PubChem CID	49831258
Molecular Weight	299.32

Certificates

Certificate of Analysis(COA)

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9 results found

Lot Number	Certificate Type	Date	Item
C2421545	Certificate of Analysis	Feb 29, 2024	M412352
C2421546	Certificate of Analysis	Feb 29, 2024	M412352
C2421547	Certificate of Analysis	Feb 29, 2024	M412352
C2421548	Certificate of Analysis	Feb 29, 2024	M412352
C2421549	Certificate of Analysis	Feb 29, 2024	M412352
C2421550	Certificate of Analysis	Feb 29, 2024	M412352
C2421551	Certificate of Analysis	Feb 29, 2024	M412352
C2421552	Certificate of Analysis	Feb 29, 2024	M412352
C2421553	Certificate of Analysis	Feb 29, 2024	M412352

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