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MRS 1706 - ≥96%(HPLC), high purity , CAS No.264622-53-9, Antagonist of A 2B receptor
Potent and selective A2Binverse agonist
Basic Description Synonyms SCHEMBL1223972 | SR-01000597590 | Acetamide, N-(4-acetylphenyl)-2-(4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy)- | A16868 | Tocris-1584 | NCGC00025221-01 | SR-01000597590-1 | N-(4-Acetyl-phenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7- Specifications & Purity Moligand™, ≥96%(HPLC) Biochemical and Physiological Mechanisms Potent and selective adenosine A2Breceptor inverse agonist (Kivalues are 1.39, 157, 112 and 230 nM for human A2B, A1, A2Aand A3receptors respectively). Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of A 2B receptor
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 488195107 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488195107 IUPAC Name N-(4-acetylphenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide INCHI InChI=1S/C27H29N5O5/c1-4-14-31-25-23(26(35)32(15-5-2)27(31)36)29-24(30-25)19-8-12-21(13-9-19)37-16-22(34)28-20-10-6-18(7-11-20)17(3)33/h6-13H,4-5,14-16H2,1-3H3,(H,28,34)(H,29,30) InChi Key ZKUCFFYOQOJLGT-UHFFFAOYSA-N Canonical SMILES CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)OCC(=O)NC4=CC=C(C=C4)C(=O)C Isomeric SMILES CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)OCC(=O)NC4=CC=C(C=C4)C(=O)C PubChem CID 5139184 Molecular Weight 503.56
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 2.52, Max Conc. mM: 5
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B2306276