Mupirocin - 10mM in DMSO, high purity , CAS No.12650-69-0

Item Number

M421107

• Synonyms: Mupirocin | 12650-69-0 | Pseudomonic acid | Bactroban | Mupirocine | Centany | Pseudomonic acid A | Bactoderm | Mupirocina | Mupirocinum | Turixin | BRL 4910A | BRL-4910A | trans-Pseudomonic acid | 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxir
• Specifications & Purity: Moligand™, 10mM in DMSO
• Biochemical and Physiological Mechanisms: Narrow spectrum antibiotic agent. Binds to isoleucyl t-RNA synthetase and inhibits protein synthesis. Shows dose dependent bacteriostatic and bactericidal effects against Gram-positive bacteria in vivo.
• Storage Temp: Store at -80°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™

Product Description

Product Describtion:

Pseudomonic Acid, also known as mupirocin, is an antibiotic isolated from Pseudomonas fluorescens which strongly inhibits protein and RNA synthesis. Inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. Pseudomonic Acid also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.
An antibiotic inhibitor of isoleucyl-tRNA synthetase

Product Application：

Mupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.